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General Information
| Manuscript title | Modeling and simulation of the redox regulation of the metabolism in Escherichia coli at different oxygen concentrations. |
| PubMed ID | 28725263 |
| Journal | Biotechnology for Biofuels |
| Year | 2017 |
| Authors | Yu Matsuoka and Hiroyuki Kurata |
| Affiliations | Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, 680 -4 Kawazu, Iizuka, Fukuoka 820 -8502, Japan |
| Keywords | Kinetic modeling, Fermentation, Dissolved oxygen limitation, Redox regulation, ArcA, Fnr, Respiratory chain, NADH/NAD+ ratio, Escherichia coli |
| Full text article |
Matsuoka_2017.pdf
|
| Project name | not specified |
| Data used for | Model building and Model validation |
Model Information
| Model name | E. coli redox regulation model | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Organism | Escherichia coli | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Associated Data EntryID |
Escherichia coli (Data EntryID:101) Escherichia coli (Data EntryID:96) |
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| Model type | ordinary differential equations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Category | Metabolism | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number of reactions | 90 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number of species | 36 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number of regulators | not specified | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number of parameters | 231 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number of compartments | 1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Dilution rate (h-1) | — | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Model file(s) and history |
LATEST KIMOMODELID40.xml
(2018-07-20 16:25:00 UTC
by Administrator KiMoSysFirst name: AdministratorAffiliation: INESC-ID/IST Homepage: http://kdbio.inesc-id.pt/kimosys Interests: mathematical modeling, accessible data, use of data )
version comment: The dissolved oxygen is set as 1%.
Preview
Preview file KIMOMODELID40.xml<?xml version='1.0' encoding='UTF-8'?>
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<model id='E_coli_Redox_Regulation_model' metaid='COPASI0' name='E_coli_Redox_Regulation_model'>
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</annotation>
<listOfFunctionDefinitions>
<functionDefinition id='Function_for_v_Acs' name='Function for v_Acs'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACT_ex </ci>
</bvar>
<bvar>
<ci> Acs_Kact </ci>
</bvar>
<bvar>
<ci> Acs_Vmax </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_CrpcAMP </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_ArcA </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Fnr </ci>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_CrpcAMP </ci>
</apply>
<ci> Acs_Vmax </ci>
<ci> ACT_ex </ci>
</apply>
<apply>
<plus/>
<ci> ACT_ex </ci>
<ci> Acs_Kact </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_ACoA' name='Function for v_D_ACoA'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACoA </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> ACoA </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_ADH' name='Function for v_ADH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> AcAld </ci>
</bvar>
<bvar>
<ci> ETH </ci>
</bvar>
<bvar>
<ci> Kacald_ADH </ci>
</bvar>
<bvar>
<ci> Keq_ADH </ci>
</bvar>
<bvar>
<ci> Keth_ADH </ci>
</bvar>
<bvar>
<ci> Knad_ADH </ci>
</bvar>
<bvar>
<ci> Knadh_ADH </ci>
</bvar>
<bvar>
<ci> NAD </ci>
</bvar>
<bvar>
<ci> NADH </ci>
</bvar>
<bvar>
<ci> Vmax_ADH </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<ci> Vmax_ADH </ci>
<apply>
<times/>
<ci> Kacald_ADH </ci>
<ci> Knadh_ADH </ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci> AcAld </ci>
<ci> NADH </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> ETH </ci>
<ci> NAD </ci>
</apply>
<ci> Keq_ADH </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> NAD </ci>
<ci> Knad_ADH </ci>
</apply>
<apply>
<divide/>
<ci> NADH </ci>
<ci> Knadh_ADH </ci>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> AcAld </ci>
<ci> Kacald_ADH </ci>
</apply>
<apply>
<divide/>
<ci> ETH </ci>
<ci> Keth_ADH </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Bio_AKG' name='Function for v_Bio_AKG'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> AKG </ci>
</bvar>
<bvar>
<ci> b_Bio_AKG </ci>
</bvar>
<bvar>
<ci> k_Bio_AKG </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<plus/>
<apply>
<times/>
<ci> k_Bio_AKG </ci>
<ci> mu </ci>
<ci> AKG </ci>
</apply>
<apply>
<times/>
<ci> b_Bio_AKG </ci>
<ci> AKG </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_CraFBP' name='Function for v_D_CraFBP'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> CraFBP </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> CraFBP </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_PYR' name='Function for v_D_PYR'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PYR </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> PYR </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Bio_ACoA' name='Function for v_Bio_ACoA'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACoA </ci>
</bvar>
<bvar>
<ci> b_Bio_ACoA </ci>
</bvar>
<bvar>
<ci> k_Bio_ACoA </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<plus/>
<apply>
<times/>
<ci> k_Bio_ACoA </ci>
<ci> mu </ci>
<ci> ACoA </ci>
</apply>
<apply>
<times/>
<ci> b_Bio_ACoA </ci>
<ci> ACoA </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_CS' name='Function for v_CS'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACoA </ci>
</bvar>
<bvar>
<ci> AKG </ci>
</bvar>
<bvar>
<ci> CS_Kacoa </ci>
</bvar>
<bvar>
<ci> CS_Kakg </ci>
</bvar>
<bvar>
<ci> CS_Koaa </ci>
</bvar>
<bvar>
<ci> CS_Koaaacoa </ci>
</bvar>
<bvar>
<ci> CS_Vmax </ci>
</bvar>
<bvar>
<ci> OAA </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_CrpcAMP </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_CrpcAMP </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_ArcA </ci>
</apply>
<ci> CS_Vmax </ci>
<ci> OAA </ci>
<ci> ACoA </ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> AKG </ci>
<ci> CS_Kakg </ci>
</apply>
</apply>
<ci> CS_Koaaacoa </ci>
<ci> CS_Kacoa </ci>
</apply>
<apply>
<times/>
<ci> CS_Kacoa </ci>
<ci> OAA </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> AKG </ci>
<ci> CS_Kakg </ci>
</apply>
</apply>
<ci> CS_Koaa </ci>
<ci> ACoA </ci>
</apply>
<apply>
<times/>
<ci> OAA </ci>
<ci> ACoA </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_CrpcAMP' name='Function for v_D_CrpcAMP'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> CrpcAMP </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> CrpcAMP </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_ACT_excretion' name='Function for v_ACT_excretion'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACoA </ci>
</bvar>
<bvar>
<ci> Mw_ACT </ci>
</bvar>
<bvar>
<ci> OD </ci>
</bvar>
<bvar>
<ci> PTACK_Kacoa </ci>
</bvar>
<bvar>
<ci> PTACK_Kpyr </ci>
</bvar>
<bvar>
<ci> PTACK_L </ci>
</bvar>
<bvar>
<ci> PTACK_Vmax </ci>
</bvar>
<bvar>
<ci> PTACK_n </ci>
</bvar>
<bvar>
<ci> PYR </ci>
</bvar>
<bvar>
<ci> uc </ci>
</bvar>
<apply>
<times/>
<ci> Mw_ACT </ci>
<ci> uc </ci>
<ci> OD </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> PTACK_Vmax </ci>
<ci> ACoA </ci>
</apply>
<ci> PTACK_Kacoa </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ACoA </ci>
<ci> PTACK_Kacoa </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> PTACK_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ACoA </ci>
<ci> PTACK_Kacoa </ci>
</apply>
</apply>
<ci> PTACK_n </ci>
</apply>
<apply>
<divide/>
<ci> PTACK_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PYR </ci>
<ci> PTACK_Kpyr </ci>
</apply>
</apply>
<ci> PTACK_n </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_Ribu5' name='Function for v_D_Ribu5'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Ribu5 </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> Ribu5 </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_S7P' name='Function for v_D_S7P'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> S7P </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> S7P </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Bio_PG3' name='Function for v_Bio_PG3'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PG3 </ci>
</bvar>
<bvar>
<ci> b_Bio_PG3 </ci>
</bvar>
<bvar>
<ci> k_Bio_PG3 </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<plus/>
<apply>
<times/>
<ci> k_Bio_PG3 </ci>
<ci> mu </ci>
<ci> PG3 </ci>
</apply>
<apply>
<times/>
<ci> b_Bio_PG3 </ci>
<ci> PG3 </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_GLCin' name='Function for v_D_GLCin'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> GLCin </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> GLCin </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_QH2' name='Function for v_D_QH2'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> QH2 </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> QH2 </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_PEP' name='Function for v_D_PEP'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> PEP </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_cAMP' name='Function for v_D_cAMP'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> cAMP </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> cAMP </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_E4P' name='Function for v_D_E4P'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> E4P </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> E4P </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_AKG' name='Function for v_D_AKG'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> AKG </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> AKG </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_NADH' name='Function for v_D_NADH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> NADH </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> NADH </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Bio_G6P' name='Function for v_Bio_G6P'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> G6P </ci>
</bvar>
<bvar>
<ci> b_Bio_G6P </ci>
</bvar>
<bvar>
<ci> k_Bio_G6P </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<plus/>
<apply>
<times/>
<ci> k_Bio_G6P </ci>
<ci> mu </ci>
<ci> G6P </ci>
</apply>
<apply>
<times/>
<ci> b_Bio_G6P </ci>
<ci> G6P </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_FOR_excretion' name='Function for v_FOR_excretion'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACoA </ci>
</bvar>
<bvar>
<ci> CoA </ci>
</bvar>
<bvar>
<ci> FOR </ci>
</bvar>
<bvar>
<ci> Kacoa_Pfl </ci>
</bvar>
<bvar>
<ci> Kcoa_Pfl </ci>
</bvar>
<bvar>
<ci> Kfor_Pfl </ci>
</bvar>
<bvar>
<ci> Kpyr_Pfl </ci>
</bvar>
<bvar>
<ci> Mw_FOR </ci>
</bvar>
<bvar>
<ci> OD </ci>
</bvar>
<bvar>
<ci> PYR </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<bvar>
<ci> Vmaxf_Pfl </ci>
</bvar>
<bvar>
<ci> Vmaxr_Pfl </ci>
</bvar>
<bvar>
<ci> uc </ci>
</bvar>
<apply>
<times/>
<ci> Mw_FOR </ci>
<ci> uc </ci>
<ci> OD </ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci> TF_Fnr </ci>
<ci> TF_ArcA </ci>
</apply>
<ci> Vmaxf_Pfl </ci>
<ci> PYR </ci>
<ci> CoA </ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> PYR </ci>
<ci> CoA </ci>
</apply>
<apply>
<times/>
<ci> Kpyr_Pfl </ci>
<ci> CoA </ci>
</apply>
<apply>
<times/>
<ci> Kcoa_Pfl </ci>
<ci> PYR </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci> TF_Fnr </ci>
<ci> TF_ArcA </ci>
</apply>
<ci> Vmaxr_Pfl </ci>
<ci> ACoA </ci>
<ci> FOR </ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> ACoA </ci>
<ci> FOR </ci>
</apply>
<apply>
<times/>
<ci> Kacoa_Pfl </ci>
<ci> FOR </ci>
</apply>
<apply>
<times/>
<ci> Kfor_Pfl </ci>
<ci> ACoA </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_KGMAL' name='Function for v_KGMAL'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> AKG </ci>
</bvar>
<bvar>
<ci> KGMAL_Kakg </ci>
</bvar>
<bvar>
<ci> KGMAL_Vmax </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_CrpcAMP </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_CrpcAMP </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_ArcA </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Fnr </ci>
</apply>
<ci> KGMAL_Vmax </ci>
<ci> AKG </ci>
</apply>
<apply>
<plus/>
<ci> AKG </ci>
<ci> KGMAL_Kakg </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_MAL' name='Function for v_D_MAL'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> MAL </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> MAL </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Bio_OAA' name='Function for v_Bio_OAA'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> OAA </ci>
</bvar>
<bvar>
<ci> b_Bio_OAA </ci>
</bvar>
<bvar>
<ci> k_Bio_OAA </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<plus/>
<apply>
<times/>
<ci> k_Bio_OAA </ci>
<ci> mu </ci>
<ci> OAA </ci>
</apply>
<apply>
<times/>
<ci> b_Bio_OAA </ci>
<ci> OAA </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Bio_E4P' name='Function for v_Bio_E4P'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> E4P </ci>
</bvar>
<bvar>
<ci> b_Bio_E4P </ci>
</bvar>
<bvar>
<ci> k_Bio_E4P </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<plus/>
<apply>
<times/>
<ci> k_Bio_E4P </ci>
<ci> mu </ci>
<ci> E4P </ci>
</apply>
<apply>
<times/>
<ci> b_Bio_E4P </ci>
<ci> E4P </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_Xyl5' name='Function for v_D_Xyl5'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Xyl5 </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> Xyl5 </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_ACT_uptake' name='Function for v_ACT_uptake'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACT_ex </ci>
</bvar>
<bvar>
<ci> Acs_Kact </ci>
</bvar>
<bvar>
<ci> Acs_Vmax </ci>
</bvar>
<bvar>
<ci> Mw_ACT </ci>
</bvar>
<bvar>
<ci> OD </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_CrpcAMP </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<bvar>
<ci> uc </ci>
</bvar>
<apply>
<times/>
<ci> Mw_ACT </ci>
<ci> uc </ci>
<ci> OD </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_ArcA </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Fnr </ci>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_CrpcAMP </ci>
</apply>
<ci> Acs_Vmax </ci>
<ci> ACT_ex </ci>
</apply>
<apply>
<plus/>
<ci> ACT_ex </ci>
<ci> Acs_Kact </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Bio_PEP' name='Function for v_Bio_PEP'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> b_Bio_PEP </ci>
</bvar>
<bvar>
<ci> k_Bio_PEP </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<plus/>
<apply>
<times/>
<ci> k_Bio_PEP </ci>
<ci> mu </ci>
<ci> PEP </ci>
</apply>
<apply>
<times/>
<ci> b_Bio_PEP </ci>
<ci> PEP </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Cyd' name='Function for v_Cyd'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Km_Cyd_O2 </ci>
</bvar>
<bvar>
<ci> Km_Cyd_QH2 </ci>
</bvar>
<bvar>
<ci> O2 </ci>
</bvar>
<bvar>
<ci> QH2 </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<bvar>
<ci> k_O2 </ci>
</bvar>
<bvar>
<ci> v_Cyd_max </ci>
</bvar>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> v_Cyd_max </ci>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_ArcA </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Fnr </ci>
</apply>
<ci> k_O2 </ci>
<ci> O2 </ci>
</apply>
<apply>
<plus/>
<ci> Km_Cyd_O2 </ci>
<apply>
<times/>
<ci> k_O2 </ci>
<ci> O2 </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<ci> QH2 </ci>
<apply>
<plus/>
<ci> Km_Cyd_QH2 </ci>
<ci> QH2 </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_ALDH' name='Function for v_ALDH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACoA </ci>
</bvar>
<bvar>
<ci> AcAld </ci>
</bvar>
<bvar>
<ci> CoA </ci>
</bvar>
<bvar>
<ci> Kacald_ALDH </ci>
</bvar>
<bvar>
<ci> Kacoa_ALDH </ci>
</bvar>
<bvar>
<ci> Kcoa_ALDH </ci>
</bvar>
<bvar>
<ci> Keq_ALDH </ci>
</bvar>
<bvar>
<ci> Knad_ALDH </ci>
</bvar>
<bvar>
<ci> Knadh_ALDH </ci>
</bvar>
<bvar>
<ci> NAD </ci>
</bvar>
<bvar>
<ci> NADH </ci>
</bvar>
<bvar>
<ci> Vmax_ALDH </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<ci> Vmax_ALDH </ci>
<apply>
<times/>
<ci> Kacoa_ALDH </ci>
<ci> Knadh_ALDH </ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci> ACoA </ci>
<ci> NADH </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> CoA </ci>
<ci> NAD </ci>
<ci> AcAld </ci>
</apply>
<ci> Keq_ALDH </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> NAD </ci>
<ci> Knad_ALDH </ci>
</apply>
<apply>
<divide/>
<ci> NADH </ci>
<ci> Knadh_ALDH </ci>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ACoA </ci>
<ci> Kacoa_ALDH </ci>
</apply>
<apply>
<divide/>
<ci> CoA </ci>
<ci> Kcoa_ALDH </ci>
</apply>
<apply>
<divide/>
<ci> AcAld </ci>
<ci> Kacald_ALDH </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> AcAld </ci>
<ci> CoA </ci>
</apply>
<apply>
<times/>
<ci> Kacald_ALDH </ci>
<ci> Kcoa_ALDH </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_ETH_excretion' name='Function for v_ETH_excretion'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> AcAld </ci>
</bvar>
<bvar>
<ci> ETH </ci>
</bvar>
<bvar>
<ci> Kacald_ADH </ci>
</bvar>
<bvar>
<ci> Keq_ADH </ci>
</bvar>
<bvar>
<ci> Keth_ADH </ci>
</bvar>
<bvar>
<ci> Knad_ADH </ci>
</bvar>
<bvar>
<ci> Knadh_ADH </ci>
</bvar>
<bvar>
<ci> Mw_ETH </ci>
</bvar>
<bvar>
<ci> NAD </ci>
</bvar>
<bvar>
<ci> NADH </ci>
</bvar>
<bvar>
<ci> OD </ci>
</bvar>
<bvar>
<ci> Vmax_ADH </ci>
</bvar>
<bvar>
<ci> uc </ci>
</bvar>
<apply>
<times/>
<ci> Mw_ETH </ci>
<ci> uc </ci>
<ci> OD </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<ci> Vmax_ADH </ci>
<apply>
<times/>
<ci> Kacald_ADH </ci>
<ci> Knadh_ADH </ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci> AcAld </ci>
<ci> NADH </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> ETH </ci>
<ci> NAD </ci>
</apply>
<ci> Keq_ADH </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> NAD </ci>
<ci> Knad_ADH </ci>
</apply>
<apply>
<divide/>
<ci> NADH </ci>
<ci> Knadh_ADH </ci>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> AcAld </ci>
<ci> Kacald_ADH </ci>
</apply>
<apply>
<divide/>
<ci> ETH </ci>
<ci> Keth_ADH </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_Rib5' name='Function for v_D_Rib5'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Rib5 </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> Rib5 </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Emp2' name='Function for v_Emp2'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Eno_Kpep </ci>
</bvar>
<bvar>
<ci> Eno_Kpg3 </ci>
</bvar>
<bvar>
<ci> Eno_Vmax_f </ci>
</bvar>
<bvar>
<ci> Eno_Vmax_r </ci>
</bvar>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> PG3 </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci> Eno_Vmax_f </ci>
<ci> PG3 </ci>
</apply>
<ci> Eno_Kpg3 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Eno_Vmax_r </ci>
<ci> PEP </ci>
</apply>
<ci> Eno_Kpep </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PG3 </ci>
<ci> Eno_Kpg3 </ci>
</apply>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Eno_Kpep </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_G6P' name='Function for v_D_G6P'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> G6P </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> G6P </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_PG6' name='Function for v_D_PG6'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PG6 </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> PG6 </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_SUC' name='Function for v_D_SUC'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> SUC </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> SUC </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_PG3' name='Function for v_D_PG3'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PG3 </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> PG3 </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Cyo' name='Function for v_Cyo'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Km_Cyo_O2 </ci>
</bvar>
<bvar>
<ci> Km_Cyo_QH2 </ci>
</bvar>
<bvar>
<ci> O2 </ci>
</bvar>
<bvar>
<ci> QH2 </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<bvar>
<ci> k_O2 </ci>
</bvar>
<bvar>
<ci> v_Cyo_max </ci>
</bvar>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> v_Cyo_max </ci>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_ArcA </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Fnr </ci>
</apply>
<ci> k_O2 </ci>
<ci> O2 </ci>
</apply>
<apply>
<plus/>
<ci> Km_Cyo_O2 </ci>
<apply>
<times/>
<ci> k_O2 </ci>
<ci> O2 </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<ci> QH2 </ci>
<apply>
<plus/>
<ci> Km_Cyo_QH2 </ci>
<ci> QH2 </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Cya' name='Function for v_Cya'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Cya_KEIIA </ci>
</bvar>
<bvar>
<ci> Cya_Vmax </ci>
</bvar>
<bvar>
<ci> EIIA_P </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<ci> Cya_Vmax </ci>
<ci> EIIA_P </ci>
</apply>
<apply>
<plus/>
<ci> EIIA_P </ci>
<ci> Cya_KEIIA </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Bio_PYR' name='Function for v_Bio_PYR'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PYR </ci>
</bvar>
<bvar>
<ci> b_Bio_PYR </ci>
</bvar>
<bvar>
<ci> k_Bio_PYR </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<plus/>
<apply>
<times/>
<ci> k_Bio_PYR </ci>
<ci> mu </ci>
<ci> PYR </ci>
</apply>
<apply>
<times/>
<ci> b_Bio_PYR </ci>
<ci> PYR </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_AcAld' name='Function for v_D_AcAld'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> AcAld </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> AcAld </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_GLX' name='Function for v_D_GLX'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> GLX </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> GLX </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Bio_R5P' name='Function for v_Bio_R5P'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Rib5 </ci>
</bvar>
<bvar>
<ci> b_Bio_R5P </ci>
</bvar>
<bvar>
<ci> k_Bio_R5P </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<plus/>
<apply>
<times/>
<ci> k_Bio_R5P </ci>
<ci> mu </ci>
<ci> Rib5 </ci>
</apply>
<apply>
<times/>
<ci> b_Bio_R5P </ci>
<ci> Rib5 </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_FBP' name='Function for v_D_FBP'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> FBP </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> FBP </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_Q' name='Function for v_D_Q'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Q </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> Q </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_PdhRPYR' name='Function for v_D_PdhRPYR'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PdhRPYR </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> PdhRPYR </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_ICT' name='Function for v_D_ICT'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ICT </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> ICT </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_FRD' name='Function for v_FRD'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Kfum_FRD </ci>
</bvar>
<bvar>
<ci> Ksuc_SDH </ci>
</bvar>
<bvar>
<ci> MAL </ci>
</bvar>
<bvar>
<ci> SUC </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<bvar>
<ci> Vmaxr_SDH </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<ci> TF_Fnr </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxr_SDH </ci>
<ci> MAL </ci>
</apply>
<ci> Kfum_FRD </ci>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> SUC </ci>
<ci> Ksuc_SDH </ci>
</apply>
<apply>
<divide/>
<ci> MAL </ci>
<ci> Kfum_FRD </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_D_OAA' name='Function for v_D_OAA'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> OAA </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> OAA </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Fdp' name='Function for v_Fdp'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> FBP </ci>
</bvar>
<bvar>
<ci> Fdp_Kfbp </ci>
</bvar>
<bvar>
<ci> Fdp_Kpep </ci>
</bvar>
<bvar>
<ci> Fdp_L </ci>
</bvar>
<bvar>
<ci> Fdp_Vmax </ci>
</bvar>
<bvar>
<ci> Fdp_n </ci>
</bvar>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<ci> Fdp_Vmax </ci>
<ci> FBP </ci>
</apply>
<ci> Fdp_Kfbp </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> FBP </ci>
<ci> Fdp_Kfbp </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> Fdp_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> FBP </ci>
<ci> Fdp_Kfbp </ci>
</apply>
</apply>
<ci> Fdp_n </ci>
</apply>
<apply>
<divide/>
<ci> Fdp_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Fdp_Kpep </ci>
</apply>
</apply>
<ci> Fdp_n </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_MDH' name='Function for v_MDH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> K_mal_MDH </ci>
</bvar>
<bvar>
<ci> K_nad_MDH </ci>
</bvar>
<bvar>
<ci> K_nadh_MDH </ci>
</bvar>
<bvar>
<ci> K_oaa_MDH </ci>
</bvar>
<bvar>
<ci> MAL </ci>
</bvar>
<bvar>
<ci> NAD </ci>
</bvar>
<bvar>
<ci> NADH </ci>
</bvar>
<bvar>
<ci> OAA </ci>
</bvar>
<bvar>
<ci> TF_CrpcAMP </ci>
</bvar>
<bvar>
<ci> Vmaxf_MDH </ci>
</bvar>
<bvar>
<ci> Vmaxr_MDH </ci>
</bvar>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_CrpcAMP </ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxf_MDH </ci>
<ci> MAL </ci>
<ci> NAD </ci>
</apply>
<apply>
<times/>
<ci> K_mal_MDH </ci>
<ci> K_nad_MDH </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxr_MDH </ci>
<ci> OAA </ci>
<ci> NADH </ci>
</apply>
<apply>
<times/>
<ci> K_oaa_MDH </ci>
<ci> K_nadh_MDH </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> MAL </ci>
<ci> K_mal_MDH </ci>
</apply>
<apply>
<divide/>
<ci> OAA </ci>
<ci> K_oaa_MDH </ci>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> NAD </ci>
<ci> K_nad_MDH </ci>
</apply>
<apply>
<divide/>
<ci> NADH </ci>
<ci> K_nadh_MDH </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Emp1' name='Function for v_Emp1'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Emp_Kfbp </ci>
</bvar>
<bvar>
<ci> Emp_Kpg3 </ci>
</bvar>
<bvar>
<ci> Emp_Vmax_f </ci>
</bvar>
<bvar>
<ci> Emp_Vmax_r </ci>
</bvar>
<bvar>
<ci> FBP </ci>
</bvar>
<bvar>
<ci> PG3 </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci> Emp_Vmax_f </ci>
<ci> FBP </ci>
</apply>
<ci> Emp_Kfbp </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Emp_Vmax_r </ci>
<ci> PG3 </ci>
</apply>
<ci> Emp_Kpg3 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> FBP </ci>
<ci> Emp_Kfbp </ci>
</apply>
<apply>
<divide/>
<ci> PG3 </ci>
<ci> Emp_Kpg3 </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_PGDH' name='Function for v_PGDH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ATP </ci>
</bvar>
<bvar>
<ci> NADP </ci>
</bvar>
<bvar>
<ci> NADPH </ci>
</bvar>
<bvar>
<ci> PG6 </ci>
</bvar>
<bvar>
<ci> PGDH_K6pg </ci>
</bvar>
<bvar>
<ci> PGDH_Katpinh </ci>
</bvar>
<bvar>
<ci> PGDH_Knadp </ci>
</bvar>
<bvar>
<ci> PGDH_Knadphinh </ci>
</bvar>
<bvar>
<ci> PGDH_Vmax </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<ci> PGDH_Vmax </ci>
<ci> mu </ci>
<cn> 10044 </cn>
<ci> PG6 </ci>
<ci> NADP </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> PG6 </ci>
<ci> PGDH_K6pg </ci>
</apply>
<apply>
<plus/>
<ci> NADP </ci>
<apply>
<times/>
<ci> PGDH_Knadp </ci>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> NADPH </ci>
<ci> PGDH_Knadphinh </ci>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ATP </ci>
<ci> PGDH_Katpinh </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_G6PDH' name='Function for v_G6PDH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> G6P </ci>
</bvar>
<bvar>
<ci> G6PDH_Kg6p </ci>
</bvar>
<bvar>
<ci> G6PDH_Knadp </ci>
</bvar>
<bvar>
<ci> G6PDH_Knadph_g6pinh </ci>
</bvar>
<bvar>
<ci> G6PDH_Knadph_nadphinh </ci>
</bvar>
<bvar>
<ci> G6PDH_Vmax </ci>
</bvar>
<bvar>
<ci> NADP </ci>
</bvar>
<bvar>
<ci> NADPH </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<ci> mu </ci>
<cn> 12202 </cn>
<ci> G6PDH_Vmax </ci>
<ci> G6P </ci>
<ci> NADP </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> G6P </ci>
<ci> G6PDH_Kg6p </ci>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> NADPH </ci>
<ci> G6PDH_Knadph_g6pinh </ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> G6PDH_Knadp </ci>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> NADPH </ci>
<ci> G6PDH_Knadph_nadphinh </ci>
</apply>
</apply>
</apply>
<ci> NADP </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Nuo' name='Function for v_Nuo'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Km_Nuo_Q </ci>
</bvar>
<bvar>
<ci> Km_Nuo_e2H2 </ci>
</bvar>
<bvar>
<ci> NADH </ci>
</bvar>
<bvar>
<ci> Q </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<bvar>
<ci> v_Nuo_max </ci>
</bvar>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> v_Nuo_max </ci>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_ArcA </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Fnr </ci>
</apply>
<ci> Q </ci>
</apply>
<apply>
<plus/>
<ci> Km_Nuo_Q </ci>
<ci> Q </ci>
</apply>
</apply>
<apply>
<divide/>
<ci> NADH </ci>
<apply>
<plus/>
<ci> Km_Nuo_e2H2 </ci>
<ci> NADH </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Ppc' name='Function for v_Ppc'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> FBP </ci>
</bvar>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> Ppc_Kfbp </ci>
</bvar>
<bvar>
<ci> Ppc_Kpep </ci>
</bvar>
<bvar>
<ci> Ppc_L </ci>
</bvar>
<bvar>
<ci> Ppc_Vmax </ci>
</bvar>
<bvar>
<ci> Ppc_n </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> Ppc_Vmax </ci>
<ci> PEP </ci>
</apply>
<ci> Ppc_Kpep </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Ppc_Kpep </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> Ppc_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Ppc_Kpep </ci>
</apply>
</apply>
<ci> Ppc_n </ci>
</apply>
<apply>
<divide/>
<ci> Ppc_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> FBP </ci>
<ci> Ppc_Kfbp </ci>
</apply>
</apply>
<ci> Ppc_n </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_NPTS' name='Function for v_NPTS'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> EIIA </ci>
</bvar>
<bvar>
<ci> GLC_ex </ci>
</bvar>
<bvar>
<ci> NPTS_Ki </ci>
</bvar>
<bvar>
<ci> NPTS_Ks </ci>
</bvar>
<bvar>
<ci> NPTS_Vmax </ci>
</bvar>
<bvar>
<ci> TF_CrpcAMP </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_CrpcAMP </ci>
</apply>
<ci> NPTS_Vmax </ci>
<ci> GLC_ex </ci>
</apply>
<apply>
<plus/>
<ci> NPTS_Ks </ci>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> EIIA </ci>
<ci> NPTS_Ki </ci>
</apply>
</apply>
<ci> GLC_ex </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_PTACK' name='Function for v_PTACK'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACoA </ci>
</bvar>
<bvar>
<ci> PTACK_Kacoa </ci>
</bvar>
<bvar>
<ci> PTACK_Kpyr </ci>
</bvar>
<bvar>
<ci> PTACK_L </ci>
</bvar>
<bvar>
<ci> PTACK_Vmax </ci>
</bvar>
<bvar>
<ci> PTACK_n </ci>
</bvar>
<bvar>
<ci> PYR </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> PTACK_Vmax </ci>
<ci> ACoA </ci>
</apply>
<ci> PTACK_Kacoa </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ACoA </ci>
<ci> PTACK_Kacoa </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> PTACK_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ACoA </ci>
<ci> PTACK_Kacoa </ci>
</apply>
</apply>
<ci> PTACK_n </ci>
</apply>
<apply>
<divide/>
<ci> PTACK_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PYR </ci>
<ci> PTACK_Kpyr </ci>
</apply>
</apply>
<ci> PTACK_n </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_PDH' name='Function for v_PDH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> GLX </ci>
</bvar>
<bvar>
<ci> PDH_Kglx </ci>
</bvar>
<bvar>
<ci> PDH_Kpyr </ci>
</bvar>
<bvar>
<ci> PDH_KpyrI </ci>
</bvar>
<bvar>
<ci> PDH_L </ci>
</bvar>
<bvar>
<ci> PDH_Vmax </ci>
</bvar>
<bvar>
<ci> PDH_n </ci>
</bvar>
<bvar>
<ci> PYR </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_PdhR </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_PdhR </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_ArcA </ci>
</apply>
<ci> PDH_Vmax </ci>
<ci> PYR </ci>
</apply>
<ci> PDH_Kpyr </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PYR </ci>
<ci> PDH_Kpyr </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> PDH_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PYR </ci>
<ci> PDH_Kpyr </ci>
</apply>
</apply>
<ci> PDH_n </ci>
</apply>
<apply>
<times/>
<ci> PDH_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> GLX </ci>
<ci> PDH_Kglx </ci>
</apply>
<apply>
<divide/>
<ci> PYR </ci>
<ci> PDH_KpyrI </ci>
</apply>
</apply>
<ci> PDH_n </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Growth' name='Function for v_Growth'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> OD </ci>
</bvar>
<bvar>
<ci> mu </ci>
</bvar>
<apply>
<times/>
<ci> OD </ci>
<ci> mu </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_TA' name='Function for v_TA'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> E4P </ci>
</bvar>
<bvar>
<ci> G6P </ci>
</bvar>
<bvar>
<ci> PG3 </ci>
</bvar>
<bvar>
<ci> S7P </ci>
</bvar>
<bvar>
<ci> TA_Keq </ci>
</bvar>
<bvar>
<ci> TA_Vmax </ci>
</bvar>
<apply>
<times/>
<ci> TA_Vmax </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> PG3 </ci>
<ci> S7P </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> E4P </ci>
<ci> G6P </ci>
</apply>
<ci> TA_Keq </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_MS' name='Function for v_MS'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACoA </ci>
</bvar>
<bvar>
<ci> GLX </ci>
</bvar>
<bvar>
<ci> MS_Kacoa </ci>
</bvar>
<bvar>
<ci> MS_Kglx </ci>
</bvar>
<bvar>
<ci> MS_Kglxacoa </ci>
</bvar>
<bvar>
<ci> MS_Vmax </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<bvar>
<ci> TF_IclR </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_IclR </ci>
</apply>
<ci> MS_Vmax </ci>
<ci> GLX </ci>
<ci> ACoA </ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> MS_Kglxacoa </ci>
<ci> MS_Kacoa </ci>
</apply>
<apply>
<times/>
<ci> MS_Kacoa </ci>
<ci> GLX </ci>
</apply>
<apply>
<times/>
<ci> MS_Kglx </ci>
<ci> ACoA </ci>
</apply>
<apply>
<times/>
<ci> GLX </ci>
<ci> ACoA </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_SUC_trans' name='Function for v_SUC_trans'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> SUC </ci>
</bvar>
<bvar>
<ci> SUC_trans_Km_suc </ci>
</bvar>
<bvar>
<ci> SUC_trans_Vmax </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<ci> SUC_trans_Vmax </ci>
<ci> SUC </ci>
</apply>
<apply>
<plus/>
<ci> SUC_trans_Km_suc </ci>
<ci> SUC </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Pfk' name='Function for v_Pfk'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> G6P </ci>
</bvar>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> Pfk_Kg6p </ci>
</bvar>
<bvar>
<ci> Pfk_Kpep </ci>
</bvar>
<bvar>
<ci> Pfk_L </ci>
</bvar>
<bvar>
<ci> Pfk_Vmax </ci>
</bvar>
<bvar>
<ci> Pfk_n </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<ci> Pfk_Vmax </ci>
<ci> G6P </ci>
</apply>
<ci> Pfk_Kg6p </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> G6P </ci>
<ci> Pfk_Kg6p </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> Pfk_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> G6P </ci>
<ci> Pfk_Kg6p </ci>
</apply>
</apply>
<ci> Pfk_n </ci>
</apply>
<apply>
<times/>
<ci> Pfk_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Pfk_Kpep </ci>
</apply>
</apply>
<ci> Pfk_n </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_TF_CraFBP' name='Function for v_TF_CraFBP'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Cra </ci>
</bvar>
<bvar>
<ci> CraFBP </ci>
</bvar>
<bvar>
<ci> FBP </ci>
</bvar>
<bvar>
<ci> TF_CraFBP_Kfbp </ci>
</bvar>
<bvar>
<ci> TF_CraFBP_n </ci>
</bvar>
<bvar>
<ci> TF_CraFBP_scale </ci>
</bvar>
<apply>
<times/>
<ci> TF_CraFBP_scale </ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci> Cra </ci>
<ci> CraFBP </ci>
</apply>
<apply>
<power/>
<ci> FBP </ci>
<ci> TF_CraFBP_n </ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci> FBP </ci>
<ci> TF_CraFBP_n </ci>
</apply>
<apply>
<power/>
<ci> TF_CraFBP_Kfbp </ci>
<ci> TF_CraFBP_n </ci>
</apply>
</apply>
</apply>
<ci> CraFBP </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Glk' name='Function for v_Glk'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> G6P </ci>
</bvar>
<bvar>
<ci> GLCin </ci>
</bvar>
<bvar>
<ci> Glk_KI </ci>
</bvar>
<bvar>
<ci> Glk_Ks </ci>
</bvar>
<bvar>
<ci> Glk_Vmax </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<ci> Glk_Vmax </ci>
<ci> GLCin </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> G6P </ci>
<ci> Glk_KI </ci>
</apply>
</apply>
<apply>
<plus/>
<ci> Glk_Ks </ci>
<ci> GLCin </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Icl' name='Function for v_Icl'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> AKG </ci>
</bvar>
<bvar>
<ci> ICT </ci>
</bvar>
<bvar>
<ci> Icl_Kakg </ci>
</bvar>
<bvar>
<ci> Icl_Kict </ci>
</bvar>
<bvar>
<ci> Icl_Kpep </ci>
</bvar>
<bvar>
<ci> Icl_Kpg3 </ci>
</bvar>
<bvar>
<ci> Icl_L </ci>
</bvar>
<bvar>
<ci> Icl_Vmax </ci>
</bvar>
<bvar>
<ci> Icl_n </ci>
</bvar>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> PG3 </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<bvar>
<ci> TF_IclR </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_IclR </ci>
</apply>
<ci> Icl_Vmax </ci>
<ci> ICT </ci>
</apply>
<ci> Icl_Kict </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ICT </ci>
<ci> Icl_Kict </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> Icl_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ICT </ci>
<ci> Icl_Kict </ci>
</apply>
</apply>
<ci> Icl_n </ci>
</apply>
<apply>
<times/>
<ci> Icl_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Icl_Kpep </ci>
</apply>
<apply>
<divide/>
<ci> PG3 </ci>
<ci> Icl_Kpg3 </ci>
</apply>
<apply>
<divide/>
<ci> AKG </ci>
<ci> Icl_Kakg </ci>
</apply>
</apply>
<ci> Icl_n </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_TKb' name='Function for v_TKb'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> E4P </ci>
</bvar>
<bvar>
<ci> G6P </ci>
</bvar>
<bvar>
<ci> PG3 </ci>
</bvar>
<bvar>
<ci> TKb_Keq </ci>
</bvar>
<bvar>
<ci> TKb_Vmax </ci>
</bvar>
<bvar>
<ci> Xyl5 </ci>
</bvar>
<apply>
<times/>
<ci> TKb_Vmax </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> Xyl5 </ci>
<ci> E4P </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> G6P </ci>
<ci> PG3 </ci>
</apply>
<ci> TKb_Keq </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Pps' name='Function for v_Pps'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> PYR </ci>
</bvar>
<bvar>
<ci> Pps_Kpep </ci>
</bvar>
<bvar>
<ci> Pps_Kpyr </ci>
</bvar>
<bvar>
<ci> Pps_L </ci>
</bvar>
<bvar>
<ci> Pps_Vmax </ci>
</bvar>
<bvar>
<ci> Pps_n </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<ci> Pps_Vmax </ci>
<ci> PYR </ci>
</apply>
<ci> Pps_Kpyr </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PYR </ci>
<ci> Pps_Kpyr </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> Pps_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PYR </ci>
<ci> Pps_Kpyr </ci>
</apply>
</apply>
<ci> Pps_n </ci>
</apply>
<apply>
<times/>
<ci> Pps_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Pps_Kpep </ci>
</apply>
</apply>
<ci> Pps_n </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_LAC_excretion' name='Function for v_LAC_excretion'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Km_NADH_LDH </ci>
</bvar>
<bvar>
<ci> Km_PYR_LDH </ci>
</bvar>
<bvar>
<ci> Mw_LAC </ci>
</bvar>
<bvar>
<ci> NADH </ci>
</bvar>
<bvar>
<ci> OD </ci>
</bvar>
<bvar>
<ci> PYR </ci>
</bvar>
<bvar>
<ci> Vmax_LDH </ci>
</bvar>
<bvar>
<ci> n_NADH_LDH </ci>
</bvar>
<bvar>
<ci> n_PYR_LDH </ci>
</bvar>
<bvar>
<ci> uc </ci>
</bvar>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> Mw_LAC </ci>
<ci> uc </ci>
<ci> OD </ci>
<ci> Vmax_LDH </ci>
<apply>
<power/>
<ci> NADH </ci>
<ci> n_NADH_LDH </ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci> Km_NADH_LDH </ci>
<ci> n_NADH_LDH </ci>
</apply>
<apply>
<power/>
<ci> NADH </ci>
<ci> n_NADH_LDH </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<apply>
<power/>
<ci> PYR </ci>
<ci> n_PYR_LDH </ci>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci> Km_PYR_LDH </ci>
<ci> n_PYR_LDH </ci>
</apply>
<apply>
<power/>
<ci> PYR </ci>
<ci> n_PYR_LDH </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Ndh' name='Function for v_Ndh'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Km_Ndh_Q </ci>
</bvar>
<bvar>
<ci> Km_Ndh_e2H2 </ci>
</bvar>
<bvar>
<ci> NADH </ci>
</bvar>
<bvar>
<ci> Q </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<bvar>
<ci> v_Ndh_max </ci>
</bvar>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> v_Ndh_max </ci>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Fnr </ci>
</apply>
<ci> Q </ci>
</apply>
<apply>
<plus/>
<ci> Km_Ndh_Q </ci>
<ci> Q </ci>
</apply>
</apply>
<apply>
<divide/>
<ci> NADH </ci>
<apply>
<plus/>
<ci> Km_Ndh_e2H2 </ci>
<ci> NADH </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Pyk' name='Function for v_Pyk'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> FBP </ci>
</bvar>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> Pyk_Kfbp </ci>
</bvar>
<bvar>
<ci> Pyk_Kpep </ci>
</bvar>
<bvar>
<ci> Pyk_L </ci>
</bvar>
<bvar>
<ci> Pyk_Vmax </ci>
</bvar>
<bvar>
<ci> Pyk_n </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<ci> Pyk_Vmax </ci>
<ci> PEP </ci>
</apply>
<ci> Pyk_Kpep </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Pyk_Kpep </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> Pyk_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Pyk_Kpep </ci>
</apply>
</apply>
<ci> Pyk_n </ci>
</apply>
<apply>
<divide/>
<ci> Pyk_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> FBP </ci>
<ci> Pyk_Kfbp </ci>
</apply>
</apply>
<ci> Pyk_n </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_LDH' name='Function for v_LDH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Km_NADH_LDH </ci>
</bvar>
<bvar>
<ci> Km_PYR_LDH </ci>
</bvar>
<bvar>
<ci> NADH </ci>
</bvar>
<bvar>
<ci> PYR </ci>
</bvar>
<bvar>
<ci> Vmax_LDH </ci>
</bvar>
<bvar>
<ci> n_NADH_LDH </ci>
</bvar>
<bvar>
<ci> n_PYR_LDH </ci>
</bvar>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmax_LDH </ci>
<apply>
<power/>
<ci> NADH </ci>
<ci> n_NADH_LDH </ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci> Km_NADH_LDH </ci>
<ci> n_NADH_LDH </ci>
</apply>
<apply>
<power/>
<ci> NADH </ci>
<ci> n_NADH_LDH </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<apply>
<power/>
<ci> PYR </ci>
<ci> n_PYR_LDH </ci>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci> Km_PYR_LDH </ci>
<ci> n_PYR_LDH </ci>
</apply>
<apply>
<power/>
<ci> PYR </ci>
<ci> n_PYR_LDH </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_syn_QH2' name='Function for v_syn_QH2'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> mu </ci>
</bvar>
<bvar>
<ci> p_syn_QH2 </ci>
</bvar>
<apply>
<times/>
<ci> mu </ci>
<ci> p_syn_QH2 </ci>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_cAMPdegr' name='Function for v_cAMPdegr'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> cAMP </ci>
</bvar>
<bvar>
<ci> cAMPdegr_KcAMP </ci>
</bvar>
<bvar>
<ci> cAMPdegr_Vmax </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<ci> cAMPdegr_Vmax </ci>
<ci> cAMP </ci>
</apply>
<apply>
<plus/>
<ci> cAMP </ci>
<ci> cAMPdegr_KcAMP </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_PTS4' name='Function for v_PTS4'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> EIIA_P </ci>
</bvar>
<bvar>
<ci> GLC_ex </ci>
</bvar>
<bvar>
<ci> PTS4_KEIIA </ci>
</bvar>
<bvar>
<ci> PTS4_Kglc </ci>
</bvar>
<bvar>
<ci> PTS4_Vmax </ci>
</bvar>
<bvar>
<ci> TF_CrpcAMP </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_CrpcAMP </ci>
</apply>
<ci> PTS4_Vmax </ci>
<ci> EIIA_P </ci>
<ci> GLC_ex </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> PTS4_KEIIA </ci>
<ci> EIIA_P </ci>
</apply>
<apply>
<plus/>
<ci> PTS4_Kglc </ci>
<ci> GLC_ex </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_GLC_uptake' name='Function for v_GLC_uptake'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> EIIA </ci>
</bvar>
<bvar>
<ci> EIIA_P </ci>
</bvar>
<bvar>
<ci> GLC_ex </ci>
</bvar>
<bvar>
<ci> Mw_GLC </ci>
</bvar>
<bvar>
<ci> NPTS_Ki </ci>
</bvar>
<bvar>
<ci> NPTS_Ks </ci>
</bvar>
<bvar>
<ci> NPTS_Vmax </ci>
</bvar>
<bvar>
<ci> OD </ci>
</bvar>
<bvar>
<ci> PTS4_KEIIA </ci>
</bvar>
<bvar>
<ci> PTS4_Kglc </ci>
</bvar>
<bvar>
<ci> PTS4_Vmax </ci>
</bvar>
<bvar>
<ci> TF_CrpcAMP </ci>
</bvar>
<bvar>
<ci> uc </ci>
</bvar>
<apply>
<times/>
<ci> Mw_GLC </ci>
<ci> uc </ci>
<ci> OD </ci>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_CrpcAMP </ci>
</apply>
<ci> PTS4_Vmax </ci>
<ci> EIIA_P </ci>
<ci> GLC_ex </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> PTS4_KEIIA </ci>
<ci> EIIA_P </ci>
</apply>
<apply>
<plus/>
<ci> PTS4_Kglc </ci>
<ci> GLC_ex </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_CrpcAMP </ci>
</apply>
<ci> NPTS_Vmax </ci>
<ci> GLC_ex </ci>
</apply>
<apply>
<plus/>
<ci> NPTS_Ks </ci>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> EIIA </ci>
<ci> NPTS_Ki </ci>
</apply>
</apply>
<ci> GLC_ex </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_SUC_excretion' name='Function for v_SUC_excretion'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Mw_SUC </ci>
</bvar>
<bvar>
<ci> OD </ci>
</bvar>
<bvar>
<ci> SUC </ci>
</bvar>
<bvar>
<ci> SUC_trans_Km_suc </ci>
</bvar>
<bvar>
<ci> SUC_trans_Vmax </ci>
</bvar>
<bvar>
<ci> uc </ci>
</bvar>
<apply>
<times/>
<ci> Mw_SUC </ci>
<ci> uc </ci>
<ci> OD </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> SUC_trans_Vmax </ci>
<ci> SUC </ci>
</apply>
<apply>
<plus/>
<ci> SUC_trans_Km_suc </ci>
<ci> SUC </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Pck' name='Function for v_Pck'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> OAA </ci>
</bvar>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> Pck_Koaa </ci>
</bvar>
<bvar>
<ci> Pck_Kpep </ci>
</bvar>
<bvar>
<ci> Pck_Vmax </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<ci> Pck_Vmax </ci>
<ci> OAA </ci>
</apply>
<apply>
<plus/>
<ci> OAA </ci>
<apply>
<times/>
<ci> Pck_Koaa </ci>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Pck_Kpep </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Pfl' name='Function for v_Pfl'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACoA </ci>
</bvar>
<bvar>
<ci> CoA </ci>
</bvar>
<bvar>
<ci> FOR </ci>
</bvar>
<bvar>
<ci> Kacoa_Pfl </ci>
</bvar>
<bvar>
<ci> Kcoa_Pfl </ci>
</bvar>
<bvar>
<ci> Kfor_Pfl </ci>
</bvar>
<bvar>
<ci> Kpyr_Pfl </ci>
</bvar>
<bvar>
<ci> PYR </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<bvar>
<ci> Vmaxf_Pfl </ci>
</bvar>
<bvar>
<ci> Vmaxr_Pfl </ci>
</bvar>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci> TF_Fnr </ci>
<ci> TF_ArcA </ci>
</apply>
<ci> Vmaxf_Pfl </ci>
<ci> PYR </ci>
<ci> CoA </ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> PYR </ci>
<ci> CoA </ci>
</apply>
<apply>
<times/>
<ci> Kpyr_Pfl </ci>
<ci> CoA </ci>
</apply>
<apply>
<times/>
<ci> Kcoa_Pfl </ci>
<ci> PYR </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci> TF_Fnr </ci>
<ci> TF_ArcA </ci>
</apply>
<ci> Vmaxr_Pfl </ci>
<ci> ACoA </ci>
<ci> FOR </ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> ACoA </ci>
<ci> FOR </ci>
</apply>
<apply>
<times/>
<ci> Kacoa_Pfl </ci>
<ci> FOR </ci>
</apply>
<apply>
<times/>
<ci> Kfor_Pfl </ci>
<ci> ACoA </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Mez' name='Function for v_Mez'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ACoA </ci>
</bvar>
<bvar>
<ci> MAL </ci>
</bvar>
<bvar>
<ci> Mez_Kacoa </ci>
</bvar>
<bvar>
<ci> Mez_Kcamp </ci>
</bvar>
<bvar>
<ci> Mez_Kmal </ci>
</bvar>
<bvar>
<ci> Mez_L </ci>
</bvar>
<bvar>
<ci> Mez_Vmax </ci>
</bvar>
<bvar>
<ci> Mez_n </ci>
</bvar>
<bvar>
<ci> cAMP </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> Mez_Vmax </ci>
<ci> MAL </ci>
</apply>
<ci> Mez_Kmal </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> MAL </ci>
<ci> Mez_Kmal </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> Mez_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> MAL </ci>
<ci> Mez_Kmal </ci>
</apply>
</apply>
<ci> Mez_n </ci>
</apply>
<apply>
<times/>
<ci> Mez_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ACoA </ci>
<ci> Mez_Kacoa </ci>
</apply>
<apply>
<divide/>
<ci> cAMP </ci>
<ci> Mez_Kcamp </ci>
</apply>
</apply>
<ci> Mez_n </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_TF_cAMPCrp' name='Function for v_TF_cAMPCrp'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Crp </ci>
</bvar>
<bvar>
<ci> CrpcAMP </ci>
</bvar>
<bvar>
<ci> TF_cAMPCrp_Kcamp </ci>
</bvar>
<bvar>
<ci> TF_cAMPCrp_n </ci>
</bvar>
<bvar>
<ci> TF_cAMPCrp_scale </ci>
</bvar>
<bvar>
<ci> cAMP </ci>
</bvar>
<apply>
<times/>
<ci> TF_cAMPCrp_scale </ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci> Crp </ci>
<ci> CrpcAMP </ci>
</apply>
<apply>
<power/>
<ci> cAMP </ci>
<ci> TF_cAMPCrp_n </ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci> cAMP </ci>
<ci> TF_cAMPCrp_n </ci>
</apply>
<apply>
<power/>
<ci> TF_cAMPCrp_Kcamp </ci>
<ci> TF_cAMPCrp_n </ci>
</apply>
</apply>
</apply>
<ci> CrpcAMP </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_R5PI' name='Function for v_R5PI'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> R5PI_Keq </ci>
</bvar>
<bvar>
<ci> R5PI_Vmax </ci>
</bvar>
<bvar>
<ci> Rib5 </ci>
</bvar>
<bvar>
<ci> Ribu5 </ci>
</bvar>
<apply>
<times/>
<ci> R5PI_Vmax </ci>
<apply>
<minus/>
<ci> Ribu5 </ci>
<apply>
<divide/>
<ci> Rib5 </ci>
<ci> R5PI_Keq </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_ICDH' name='Function for v_ICDH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> ICDH_Kict </ci>
</bvar>
<bvar>
<ci> ICDH_Kpep </ci>
</bvar>
<bvar>
<ci> ICDH_L </ci>
</bvar>
<bvar>
<ci> ICDH_Vmax </ci>
</bvar>
<bvar>
<ci> ICDH_n </ci>
</bvar>
<bvar>
<ci> ICT </ci>
</bvar>
<bvar>
<ci> PEP </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_Cra </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_Cra </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_ArcA </ci>
</apply>
<ci> ICDH_Vmax </ci>
<ci> ICT </ci>
</apply>
<ci> ICDH_Kict </ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ICT </ci>
<ci> ICDH_Kict </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> ICDH_n </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> ICT </ci>
<ci> ICDH_Kict </ci>
</apply>
</apply>
<ci> ICDH_n </ci>
</apply>
<apply>
<times/>
<ci> ICDH_L </ci>
<apply>
<power/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> ICDH_Kpep </ci>
</apply>
</apply>
<ci> ICDH_n </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_Ru5P' name='Function for v_Ru5P'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Ribu5 </ci>
</bvar>
<bvar>
<ci> Ru5P_Keq </ci>
</bvar>
<bvar>
<ci> Ru5P_Vmax </ci>
</bvar>
<bvar>
<ci> Xyl5 </ci>
</bvar>
<apply>
<times/>
<ci> Ru5P_Vmax </ci>
<apply>
<minus/>
<ci> Ribu5 </ci>
<apply>
<divide/>
<ci> Xyl5 </ci>
<ci> Ru5P_Keq </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_TF_PdhRPYR' name='Function for v_TF_PdhRPYR'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PYR </ci>
</bvar>
<bvar>
<ci> PdhR </ci>
</bvar>
<bvar>
<ci> PdhRPYR </ci>
</bvar>
<bvar>
<ci> TF_PdhRPYR_Kpyr </ci>
</bvar>
<bvar>
<ci> TF_PdhRPYR_n </ci>
</bvar>
<bvar>
<ci> TF_PdhRPYR_scale </ci>
</bvar>
<apply>
<times/>
<ci> TF_PdhRPYR_scale </ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci> PdhR </ci>
<ci> PdhRPYR </ci>
</apply>
<apply>
<power/>
<ci> PYR </ci>
<ci> TF_PdhRPYR_n </ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci> PYR </ci>
<ci> TF_PdhRPYR_n </ci>
</apply>
<apply>
<power/>
<ci> TF_PdhRPYR_Kpyr </ci>
<ci> TF_PdhRPYR_n </ci>
</apply>
</apply>
</apply>
<ci> PdhRPYR </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_SDH' name='Function for v_SDH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> Kfum_SDH </ci>
</bvar>
<bvar>
<ci> Ksuc_SDH </ci>
</bvar>
<bvar>
<ci> MAL </ci>
</bvar>
<bvar>
<ci> SUC </ci>
</bvar>
<bvar>
<ci> TF_ArcA </ci>
</bvar>
<bvar>
<ci> TF_CrpcAMP </ci>
</bvar>
<bvar>
<ci> TF_Fnr </ci>
</bvar>
<bvar>
<ci> Vmaxf_SDH </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_Fnr </ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<ci> TF_ArcA </ci>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<ci> TF_CrpcAMP </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxf_SDH </ci>
<ci> SUC </ci>
</apply>
<ci> Ksuc_SDH </ci>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> SUC </ci>
<ci> Ksuc_SDH </ci>
</apply>
<apply>
<divide/>
<ci> MAL </ci>
<ci> Kfum_SDH </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id='Function_for_v_TKa' name='Function for v_TKa'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<lambda>
<bvar>
<ci> PG3 </ci>
</bvar>
<bvar>
<ci> Rib5 </ci>
</bvar>
<bvar>
<ci> S7P </ci>
</bvar>
<bvar>
<ci> TKa_Keq </ci>
</bvar>
<bvar>
<ci> TKa_Vmax </ci>
</bvar>
<bvar>
<ci> Xyl5 </ci>
</bvar>
<apply>
<times/>
<ci> TKa_Vmax </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> Rib5 </ci>
<ci> Xyl5 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> S7P </ci>
<ci> PG3 </ci>
</apply>
<ci> TKa_Keq </ci>
</apply>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
</listOfFunctionDefinitions>
<listOfCompartments>
<compartment constant='true' id='default' name='default' size='1' spatialDimensions='0'/>
</listOfCompartments>
<listOfSpecies>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='ACT_ex' initialConcentration='4.41171563e-020' name='ACT_ex'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='ACoA' initialConcentration='4.70001728' name='ACoA'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='AKG' initialConcentration='0.00726754307' name='AKG'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='AcAld' initialConcentration='60.7619995' name='AcAld'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='CraFBP' initialConcentration='0.00710065667' name='CraFBP'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='CrpcAMP' initialConcentration='0.00202615063' name='CrpcAMP'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='E4P' initialConcentration='2.13073785' name='E4P'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='EIIA' initialConcentration='0.0939545839' name='EIIA'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='EIIA_P' initialConcentration='0.0060454161' name='EIIA_P'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='ETH' initialConcentration='3.84983883e-020' name='ETH'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='FBP' initialConcentration='8.32853641' name='FBP'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='FOR' initialConcentration='7.55387574e-020' name='FOR'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='G6P' initialConcentration='2.91761046' name='G6P'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='GLC_ex' initialConcentration='10' name='GLC_ex'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='GLCin' initialConcentration='0.00125019263' name='GLCin'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='GLX' initialConcentration='2.07001687e-006' name='GLX'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='ICT' initialConcentration='0.00135758827' name='ICT'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='LAC' initialConcentration='2.62515096e-021' name='LAC'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='MAL' initialConcentration='6.40435745' name='MAL'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='NADH' initialConcentration='5.19361024' name='NADH'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='OAA' initialConcentration='0.0162480847' name='OAA'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='OD' initialConcentration='0.03' name='OD'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='PEP' initialConcentration='0.299818019' name='PEP'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='PG3' initialConcentration='9.61305771' name='PG3'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='PG6' initialConcentration='0.896449518' name='PG6'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='PYR' initialConcentration='1.09523254' name='PYR'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='PdhRPYR' initialConcentration='0.00634056037' name='PdhRPYR'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='Q' initialConcentration='0.155436748' name='Q'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='QH2' initialConcentration='1.98975228' name='QH2'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='Rib5' initialConcentration='3.75050913' name='Rib5'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='Ribu5' initialConcentration='0.944205944' name='Ribu5'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='S7P' initialConcentration='0.616060896' name='S7P'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='SUC' initialConcentration='19.8809191' name='SUC'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='SUC_ex' initialConcentration='1.10353343e-020' name='SUC_ex'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='Xyl5' initialConcentration='1.31636167' name='Xyl5'/>
<species boundaryCondition='false' compartment='default' constant='false' hasOnlySubstanceUnits='false' id='cAMP' initialConcentration='0.344501653' name='cAMP'/>
</listOfSpecies>
<listOfParameters>
<parameter constant='true' id='ATP' name='ATP' value='7.5709'/>
<parameter constant='true' id='Acs_Kact' name='Acs_Kact' value='0.001'/>
<parameter constant='true' id='Acs_Vmax' name='Acs_Vmax' value='0.7294'/>
<parameter constant='true' id='CS_Kacoa' name='CS_Kacoa' value='0.212'/>
<parameter constant='true' id='CS_Kakg' name='CS_Kakg' value='0.63'/>
<parameter constant='true' id='CS_Koaa' name='CS_Koaa' value='0.029'/>
<parameter constant='true' id='CS_Koaaacoa' name='CS_Koaaacoa' value='0.029'/>
<parameter constant='true' id='CS_Vmax' name='CS_Vmax' value='2.1154'/>
<parameter constant='true' id='CoA' name='CoA' value='0.8865'/>
<parameter constant='false' id='Cra' name='Cra' value='0.00018934333'/>
<parameter constant='true' id='Cra_total' name='Cra_total' value='0.00729'/>
<parameter constant='false' id='Crp' name='Crp' value='0.00526384937'/>
<parameter constant='true' id='Crp_total' name='Crp_total' value='0.00729'/>
<parameter constant='true' id='Cya_KEIIA' name='Cya_KEIIA' value='0.0017'/>
<parameter constant='true' id='Cya_Vmax' name='Cya_Vmax' value='0.993'/>
<parameter constant='true' id='Emp_Kfbp' name='Emp_Kfbp' value='5.92'/>
<parameter constant='true' id='Emp_Kpg3' name='Emp_Kpg3' value='16.6'/>
<parameter constant='true' id='Emp_Vmax_f' name='Emp_Vmax_f' value='10.194683'/>
<parameter constant='true' id='Emp_Vmax_r' name='Emp_Vmax_r' value='10.194683'/>
<parameter constant='true' id='Eno_Kpep' name='Eno_Kpep' value='1.11'/>
<parameter constant='true' id='Eno_Kpg3' name='Eno_Kpg3' value='4.76'/>
<parameter constant='true' id='Eno_Vmax_f' name='Eno_Vmax_f' value='10.194683'/>
<parameter constant='true' id='Eno_Vmax_r' name='Eno_Vmax_r' value='10.194683'/>
<parameter constant='true' id='Fdp_Kfbp' name='Fdp_Kfbp' value='0.003'/>
<parameter constant='true' id='Fdp_Kpep' name='Fdp_Kpep' value='0.3'/>
<parameter constant='true' id='Fdp_L' name='Fdp_L' value='4000000'/>
<parameter constant='true' id='Fdp_Vmax' name='Fdp_Vmax' value='0.114'/>
<parameter constant='true' id='Fdp_n' name='Fdp_n' value='4'/>
<parameter constant='true' id='G6PDH_Kg6p' name='G6PDH_Kg6p' value='25.5319'/>
<parameter constant='true' id='G6PDH_Knadp' name='G6PDH_Knadp' value='0.0436'/>
<parameter constant='true' id='G6PDH_Knadph_g6pinh' name='G6PDH_Knadph_g6pinh' value='11.4007'/>
<parameter constant='true' id='G6PDH_Knadph_nadphinh' name='G6PDH_Knadph_nadphinh' value='0.0177'/>
<parameter constant='true' id='G6PDH_Vmax' name='G6PDH_Vmax' value='2.4472'/>
<parameter constant='true' id='Glk_KI' name='Glk_KI' value='0.1'/>
<parameter constant='true' id='Glk_Ks' name='Glk_Ks' value='16'/>
<parameter constant='true' id='Glk_Vmax' name='Glk_Vmax' value='5.556'/>
<parameter constant='true' id='ICDH_Kict' name='ICDH_Kict' value='0.00016'/>
<parameter constant='true' id='ICDH_Kpep' name='ICDH_Kpep' value='0.334'/>
<parameter constant='true' id='ICDH_L' name='ICDH_L' value='127'/>
<parameter constant='true' id='ICDH_Vmax' name='ICDH_Vmax' value='7.8873'/>
<parameter constant='true' id='ICDH_n' name='ICDH_n' value='2'/>
<parameter constant='true' id='Icl_Kakg' name='Icl_Kakg' value='0.827'/>
<parameter constant='true' id='Icl_Kict' name='Icl_Kict' value='0.0022'/>
<parameter constant='true' id='Icl_Kpep' name='Icl_Kpep' value='0.055'/>
<parameter constant='true' id='Icl_Kpg3' name='Icl_Kpg3' value='0.72'/>
<parameter constant='true' id='Icl_L' name='Icl_L' value='5.01'/>
<parameter constant='true' id='Icl_Vmax' name='Icl_Vmax' value='1.2324'/>
<parameter constant='true' id='Icl_n' name='Icl_n' value='4'/>
<parameter constant='true' id='KGMAL_Kakg' name='KGMAL_Kakg' value='0.548'/>
<parameter constant='true' id='KGMAL_Vmax' name='KGMAL_Vmax' value='1.1832'/>
<parameter constant='true' id='K_A_ArcA_Q' name='K_A_ArcA_Q' value='0.5'/>
<parameter constant='true' id='K_A_FNR_O2' name='K_A_FNR_O2' value='5e-006'/>
<parameter constant='true' id='K_Cra' name='K_Cra' value='0.015'/>
<parameter constant='true' id='K_CrpcAMP' name='K_CrpcAMP' value='0.0012'/>
<parameter constant='true' id='K_IclR' name='K_IclR' value='0.003'/>
<parameter constant='true' id='K_PdhR' name='K_PdhR' value='0.001'/>
<parameter constant='true' id='K_mal_MDH' name='K_mal_MDH' value='29.8'/>
<parameter constant='true' id='K_nad_MDH' name='K_nad_MDH' value='29.8851'/>
<parameter constant='true' id='K_nadh_MDH' name='K_nadh_MDH' value='7.0115'/>
<parameter constant='true' id='K_oaa_MDH' name='K_oaa_MDH' value='0.56322'/>
<parameter constant='true' id='Kacald_ADH' name='Kacald_ADH' value='0.0532'/>
<parameter constant='true' id='Kacald_ALDH' name='Kacald_ALDH' value='17.7305'/>
<parameter constant='true' id='Kacoa_ALDH' name='Kacoa_ALDH' value='0.0124'/>
<parameter constant='true' id='Kacoa_Pfl' name='Kacoa_Pfl' value='5.8621'/>
<parameter constant='true' id='Kcoa_ALDH' name='Kcoa_ALDH' value='0.0142'/>
<parameter constant='true' id='Kcoa_Pfl' name='Kcoa_Pfl' value='0.7816'/>
<parameter constant='true' id='Keq_ADH' name='Keq_ADH' value='21906'/>
<parameter constant='true' id='Keq_ALDH' name='Keq_ALDH' value='27.73'/>
<parameter constant='true' id='Keth_ADH' name='Keth_ADH' value='0.00071065'/>
<parameter constant='true' id='Kfor_Pfl' name='Kfor_Pfl' value='1.1276'/>
<parameter constant='true' id='Kfum_FRD' name='Kfum_FRD' value='0.5747'/>
<parameter constant='true' id='Kfum_SDH' name='Kfum_SDH' value='0.5747'/>
<parameter constant='true' id='Km_Cyd_O2' name='Km_Cyd_O2' value='2.4e-005'/>
<parameter constant='true' id='Km_Cyd_QH2' name='Km_Cyd_QH2' value='10'/>
<parameter constant='true' id='Km_Cyo_O2' name='Km_Cyo_O2' value='0.0002'/>
<parameter constant='true' id='Km_Cyo_QH2' name='Km_Cyo_QH2' value='25'/>
<parameter constant='true' id='Km_NADH_LDH' name='Km_NADH_LDH' value='0.9'/>
<parameter constant='true' id='Km_Ndh_Q' name='Km_Ndh_Q' value='0.34'/>
<parameter constant='true' id='Km_Ndh_e2H2' name='Km_Ndh_e2H2' value='20'/>
<parameter constant='true' id='Km_Nuo_Q' name='Km_Nuo_Q' value='0.34'/>
<parameter constant='true' id='Km_Nuo_e2H2' name='Km_Nuo_e2H2' value='20'/>
<parameter constant='true' id='Km_PYR_LDH' name='Km_PYR_LDH' value='26.7'/>
<parameter constant='true' id='Knad_ADH' name='Knad_ADH' value='0.1418'/>
<parameter constant='true' id='Knad_ALDH' name='Knad_ALDH' value='0.1418'/>
<parameter constant='true' id='Knadh_ADH' name='Knadh_ADH' value='2.1'/>
<parameter constant='true' id='Knadh_ALDH' name='Knadh_ALDH' value='0.443'/>
<parameter constant='true' id='Kpyr_Pfl' name='Kpyr_Pfl' value='4.5'/>
<parameter constant='true' id='Ksuc_SDH' name='Ksuc_SDH' value='0.2299'/>
<parameter constant='true' id='MS_Kacoa' name='MS_Kacoa' value='0.755'/>
<parameter constant='true' id='MS_Kglx' name='MS_Kglx' value='0.95'/>
<parameter constant='true' id='MS_Kglxacoa' name='MS_Kglxacoa' value='0.719'/>
<parameter constant='true' id='MS_Vmax' name='MS_Vmax' value='2.1444'/>
<parameter constant='true' id='Mez_Kacoa' name='Mez_Kacoa' value='3.64'/>
<parameter constant='true' id='Mez_Kcamp' name='Mez_Kcamp' value='6.54'/>
<parameter constant='true' id='Mez_Kmal' name='Mez_Kmal' value='0.00624'/>
<parameter constant='true' id='Mez_L' name='Mez_L' value='104000'/>
<parameter constant='true' id='Mez_Vmax' name='Mez_Vmax' value='0.70745'/>
<parameter constant='true' id='Mez_n' name='Mez_n' value='1.33'/>
<parameter constant='true' id='Mw_ACT' name='Mw_ACT' value='60.05'/>
<parameter constant='true' id='Mw_ETH' name='Mw_ETH' value='46.07'/>
<parameter constant='true' id='Mw_FOR' name='Mw_FOR' value='46.025'/>
<parameter constant='true' id='Mw_GLC' name='Mw_GLC' value='180.156'/>
<parameter constant='true' id='Mw_LAC' name='Mw_LAC' value='90.08'/>
<parameter constant='true' id='Mw_SUC' name='Mw_SUC' value='118.09'/>
<parameter constant='false' id='NAD' name='NAD' value='7.70638976'/>
<parameter constant='true' id='NADH_NAD_total' name='NADH_NAD_total' value='12.9'/>
<parameter constant='true' id='NADP' name='NADP' value='0.3457'/>
<parameter constant='true' id='NADPH' name='NADPH' value='0.1099'/>
<parameter constant='true' id='NPTS_Ki' name='NPTS_Ki' value='5e-006'/>
<parameter constant='true' id='NPTS_Ks' name='NPTS_Ks' value='0.01'/>
<parameter constant='true' id='NPTS_Vmax' name='NPTS_Vmax' value='0.167'/>
<parameter constant='true' id='O2' name='O2' value='0.0021'/>
<parameter constant='false' id='OP_NADH' name='OP_NADH' value='0'/>
<parameter constant='true' id='PDH_Kglx' name='PDH_Kglx' value='0.218'/>
<parameter constant='true' id='PDH_Kpyr' name='PDH_Kpyr' value='0.128'/>
<parameter constant='true' id='PDH_KpyrI' name='PDH_KpyrI' value='0.231'/>
<parameter constant='true' id='PDH_L' name='PDH_L' value='3.4'/>
<parameter constant='true' id='PDH_Vmax' name='PDH_Vmax' value='5.6667'/>
<parameter constant='true' id='PDH_n' name='PDH_n' value='2.65'/>
<parameter constant='true' id='PGDH_K6pg' name='PGDH_K6pg' value='66.4894'/>
<parameter constant='true' id='PGDH_Katpinh' name='PGDH_Katpinh' value='368.7943'/>
<parameter constant='true' id='PGDH_Knadp' name='PGDH_Knadp' value='0.0897'/>
<parameter constant='true' id='PGDH_Knadphinh' name='PGDH_Knadphinh' value='0.0245'/>
<parameter constant='true' id='PGDH_Vmax' name='PGDH_Vmax' value='28.7808'/>
<parameter constant='true' id='PTACK_Kacoa' name='PTACK_Kacoa' value='0.022'/>
<parameter constant='true' id='PTACK_Kpyr' name='PTACK_Kpyr' value='0.022'/>
<parameter constant='true' id='PTACK_L' name='PTACK_L' value='639000'/>
<parameter constant='true' id='PTACK_Vmax' name='PTACK_Vmax' value='2.2'/>
<parameter constant='true' id='PTACK_n' name='PTACK_n' value='2'/>
<parameter constant='true' id='PTS1_k1' name='PTS1_k1' value='116'/>
<parameter constant='true' id='PTS1_km1' name='PTS1_km1' value='46.3'/>
<parameter constant='true' id='PTS4_KEIIA' name='PTS4_KEIIA' value='0.0085'/>
<parameter constant='true' id='PTS4_Kglc' name='PTS4_Kglc' value='0.0012'/>
<parameter constant='true' id='PTS4_Vmax' name='PTS4_Vmax' value='4.3766'/>
<parameter constant='true' id='Pck_Koaa' name='Pck_Koaa' value='0.184'/>
<parameter constant='true' id='Pck_Kpep' name='Pck_Kpep' value='1000'/>
<parameter constant='true' id='Pck_Vmax' name='Pck_Vmax' value='0.0872'/>
<parameter constant='false' id='PdhR' name='PdhR' value='0.000949439630000001'/>
<parameter constant='true' id='PdhR_total' name='PdhR_total' value='0.00729'/>
<parameter constant='true' id='Pfk_Kg6p' name='Pfk_Kg6p' value='0.022'/>
<parameter constant='true' id='Pfk_Kpep' name='Pfk_Kpep' value='0.138'/>
<parameter constant='true' id='Pfk_L' name='Pfk_L' value='95000000'/>
<parameter constant='true' id='Pfk_Vmax' name='Pfk_Vmax' value='92.510592'/>
<parameter constant='true' id='Pfk_n' name='Pfk_n' value='4'/>
<parameter constant='true' id='Ppc_Kfbp' name='Ppc_Kfbp' value='0.408'/>
<parameter constant='true' id='Ppc_Kpep' name='Ppc_Kpep' value='0.048'/>
<parameter constant='true' id='Ppc_L' name='Ppc_L' value='5200000'/>
<parameter constant='true' id='Ppc_Vmax' name='Ppc_Vmax' value='1'/>
<parameter constant='true' id='Ppc_n' name='Ppc_n' value='3'/>
<parameter constant='true' id='Pps_Kpep' name='Pps_Kpep' value='0.001'/>
<parameter constant='true' id='Pps_Kpyr' name='Pps_Kpyr' value='0.00177'/>
<parameter constant='true' id='Pps_L' name='Pps_L' value='1e-079'/>
<parameter constant='true' id='Pps_Vmax' name='Pps_Vmax' value='0.0041'/>
<parameter constant='true' id='Pps_n' name='Pps_n' value='2'/>
<parameter constant='true' id='Pyk_Kfbp' name='Pyk_Kfbp' value='0.413'/>
<parameter constant='true' id='Pyk_Kpep' name='Pyk_Kpep' value='5'/>
<parameter constant='true' id='Pyk_L' name='Pyk_L' value='100000'/>
<parameter constant='true' id='Pyk_Vmax' name='Pyk_Vmax' value='49.501994'/>
<parameter constant='true' id='Pyk_n' name='Pyk_n' value='4'/>
<parameter constant='true' id='R5PI_Keq' name='R5PI_Keq' value='4'/>
<parameter constant='true' id='R5PI_Vmax' name='R5PI_Vmax' value='8.5787'/>
<parameter constant='true' id='Ru5P_Keq' name='Ru5P_Keq' value='1.4'/>
<parameter constant='true' id='Ru5P_Vmax' name='Ru5P_Vmax' value='11.9486'/>
<parameter constant='true' id='SUC_trans_Km_suc' name='SUC_trans_Km_suc' value='16'/>
<parameter constant='true' id='SUC_trans_Vmax' name='SUC_trans_Vmax' value='0.5'/>
<parameter constant='true' id='TA_Keq' name='TA_Keq' value='1.05'/>
<parameter constant='true' id='TA_Vmax' name='TA_Vmax' value='19.276'/>
<parameter constant='false' id='TF_ArcA' name='TF_ArcA' value='0.997104928136151'/>
<parameter constant='false' id='TF_Cra' name='TF_Cra' value='0.0124655375737037'/>
<parameter constant='true' id='TF_CraFBP_Kfbp' name='TF_CraFBP_Kfbp' value='1.36'/>
<parameter constant='true' id='TF_CraFBP_n' name='TF_CraFBP_n' value='2'/>
<parameter constant='true' id='TF_CraFBP_scale' name='TF_CraFBP_scale' value='100'/>
<parameter constant='false' id='TF_CrpcAMP' name='TF_CrpcAMP' value='0.628039686417246'/>
<parameter constant='false' id='TF_Fnr' name='TF_Fnr' value='0.987099475346047'/>
<parameter constant='false' id='TF_IclR' name='TF_IclR' value='0.764484246066118'/>
<parameter constant='false' id='TF_PdhR' name='TF_PdhR' value='0.487032075981753'/>
<parameter constant='true' id='TF_PdhRPYR_Kpyr' name='TF_PdhRPYR_Kpyr' value='0.164'/>
<parameter constant='true' id='TF_PdhRPYR_n' name='TF_PdhRPYR_n' value='1'/>
<parameter constant='true' id='TF_PdhRPYR_scale' name='TF_PdhRPYR_scale' value='100'/>
<parameter constant='true' id='TF_cAMPCrp_Kcamp' name='TF_cAMPCrp_Kcamp' value='0.895'/>
<parameter constant='true' id='TF_cAMPCrp_n' name='TF_cAMPCrp_n' value='1'/>
<parameter constant='true' id='TF_cAMPCrp_scale' name='TF_cAMPCrp_scale' value='100000000'/>
<parameter constant='true' id='TKa_Keq' name='TKa_Keq' value='1.2'/>
<parameter constant='true' id='TKa_Vmax' name='TKa_Vmax' value='16.7968'/>
<parameter constant='true' id='TKb_Keq' name='TKb_Keq' value='10'/>
<parameter constant='true' id='TKb_Vmax' name='TKb_Vmax' value='153.4726'/>
<parameter constant='true' id='Vmax_ADH' name='Vmax_ADH' value='57.97'/>
<parameter constant='true' id='Vmax_ALDH' name='Vmax_ALDH' value='63.9'/>
<parameter constant='true' id='Vmax_LDH' name='Vmax_LDH' value='51.7'/>
<parameter constant='true' id='Vmaxf_MDH' name='Vmaxf_MDH' value='12.677'/>
<parameter constant='true' id='Vmaxf_Pfl' name='Vmaxf_Pfl' value='14.7'/>
<parameter constant='true' id='Vmaxf_SDH' name='Vmaxf_SDH' value='1.8101'/>
<parameter constant='true' id='Vmaxr_MDH' name='Vmaxr_MDH' value='54.3318'/>
<parameter constant='true' id='Vmaxr_Pfl' name='Vmaxr_Pfl' value='3.4'/>
<parameter constant='true' id='Vmaxr_SDH' name='Vmaxr_SDH' value='2.5'/>
<parameter constant='true' id='b_Bio_ACoA' name='b_Bio_ACoA' value='0.035'/>
<parameter constant='true' id='b_Bio_AKG' name='b_Bio_AKG' value='0.002'/>
<parameter constant='true' id='b_Bio_E4P' name='b_Bio_E4P' value='0.002'/>
<parameter constant='true' id='b_Bio_G6P' name='b_Bio_G6P' value='0.002'/>
<parameter constant='true' id='b_Bio_OAA' name='b_Bio_OAA' value='0.002'/>
<parameter constant='true' id='b_Bio_PEP' name='b_Bio_PEP' value='0.002'/>
<parameter constant='true' id='b_Bio_PG3' name='b_Bio_PG3' value='0.002'/>
<parameter constant='true' id='b_Bio_PYR' name='b_Bio_PYR' value='0.002'/>
<parameter constant='true' id='b_Bio_R5P' name='b_Bio_R5P' value='0.002'/>
<parameter constant='true' id='cAMPdegr_KcAMP' name='cAMPdegr_KcAMP' value='0.1'/>
<parameter constant='true' id='cAMPdegr_Vmax' name='cAMPdegr_Vmax' value='1'/>
<parameter constant='true' id='k_ATP' name='k_ATP' value='1e-005'/>
<parameter constant='true' id='k_Bio_ACoA' name='k_Bio_ACoA' value='135.36'/>
<parameter constant='true' id='k_Bio_AKG' name='k_Bio_AKG' value='7041.6'/>
<parameter constant='true' id='k_Bio_E4P' name='k_Bio_E4P' value='72'/>
<parameter constant='true' id='k_Bio_G6P' name='k_Bio_G6P' value='554.4'/>
<parameter constant='true' id='k_Bio_OAA' name='k_Bio_OAA' value='46080'/>
<parameter constant='true' id='k_Bio_PEP' name='k_Bio_PEP' value='3045.6'/>
<parameter constant='true' id='k_Bio_PG3' name='k_Bio_PG3' value='352.8'/>
<parameter constant='true' id='k_Bio_PYR' name='k_Bio_PYR' value='39.816'/>
<parameter constant='true' id='k_Bio_R5P' name='k_Bio_R5P' value='72'/>
<parameter constant='true' id='k_O2' name='k_O2' value='0.001'/>
<parameter constant='false' id='mu' name='mu' value='0'/>
<parameter constant='true' id='n_ArcA' name='n_ArcA' value='-5'/>
<parameter constant='true' id='n_FNR' name='n_FNR' value='-5'/>
<parameter constant='true' id='n_IclR' name='n_IclR' value='-3'/>
<parameter constant='true' id='n_NADH_LDH' name='n_NADH_LDH' value='3'/>
<parameter constant='true' id='n_PYR_LDH' name='n_PYR_LDH' value='2'/>
<parameter constant='true' id='p_syn_QH2' name='p_syn_QH2' value='2.16'/>
<parameter constant='true' id='uc' name='uc' value='9.5e-007'/>
<parameter constant='false' id='v_ATP' name='v_ATP' value='0'/>
<parameter constant='true' id='v_Cyd_max' name='v_Cyd_max' value='31.5582'/>
<parameter constant='true' id='v_Cyo_max' name='v_Cyo_max' value='800'/>
<parameter constant='true' id='v_Ndh_max' name='v_Ndh_max' value='11.1111'/>
<parameter constant='true' id='v_Nuo_max' name='v_Nuo_max' value='708.3333'/>
</listOfParameters>
<listOfRules>
<assignmentRule variable='Cra'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<minus/>
<ci> Cra_total </ci>
<ci> CraFBP </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='Crp'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<minus/>
<ci> Crp_total </ci>
<ci> CrpcAMP </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='TF_CrpcAMP'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<ci> CrpcAMP </ci>
<apply>
<plus/>
<ci> CrpcAMP </ci>
<ci> K_CrpcAMP </ci>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='TF_Fnr'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<power/>
<apply>
<times/>
<ci> k_O2 </ci>
<ci> O2 </ci>
</apply>
<ci> n_FNR </ci>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci> K_A_FNR_O2 </ci>
<ci> n_FNR </ci>
</apply>
<apply>
<power/>
<apply>
<times/>
<ci> k_O2 </ci>
<ci> O2 </ci>
</apply>
<ci> n_FNR </ci>
</apply>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='TF_Cra'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<ci> Cra </ci>
<apply>
<plus/>
<ci> Cra </ci>
<ci> K_Cra </ci>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='TF_IclR'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<power/>
<ci> CrpcAMP </ci>
<ci> n_IclR </ci>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci> K_IclR </ci>
<ci> n_IclR </ci>
</apply>
<apply>
<power/>
<ci> CrpcAMP </ci>
<ci> n_IclR </ci>
</apply>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='TF_ArcA'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<power/>
<ci> Q </ci>
<ci> n_ArcA </ci>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci> K_A_ArcA_Q </ci>
<ci> n_ArcA </ci>
</apply>
<apply>
<power/>
<ci> Q </ci>
<ci> n_ArcA </ci>
</apply>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='PdhR'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<minus/>
<ci> PdhR_total </ci>
<ci> PdhRPYR </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='TF_PdhR'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<ci> PdhR </ci>
<apply>
<plus/>
<ci> PdhR </ci>
<ci> K_PdhR </ci>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='NAD'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<minus/>
<ci> NADH_NAD_total </ci>
<ci> NADH </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='OP_NADH'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<times/>
<cn> 4 </cn>
<ci> v_Nuo </ci>
</apply>
<apply>
<times/>
<cn> 4 </cn>
<ci> v_Cyo </ci>
</apply>
<apply>
<times/>
<cn> 2 </cn>
<ci> v_Cyd </ci>
</apply>
</apply>
<cn> 3 </cn>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='v_ATP'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<plus/>
<ci> OP_NADH </ci>
<ci> v_Emp2 </ci>
<ci> v_Pyk </ci>
<ci> v_PTACK </ci>
<ci> v_KGMAL </ci>
</apply>
<ci> v_Pfk </ci>
</apply>
<ci> v_Pck </ci>
</apply>
<ci> v_Acs </ci>
</apply>
<ci> v_Glk </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable='mu'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> k_ATP </ci>
<ci> v_ATP </ci>
</apply>
</math>
</assignmentRule>
</listOfRules>
<listOfReactions>
<reaction id='v_ACT_excretion' name='v_ACT_excretion' reversible='true'>
<listOfProducts>
<speciesReference species='ACT_ex' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='ACoA'/>
<modifierSpeciesReference species='PYR'/>
<modifierSpeciesReference species='OD'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_ACT_excretion </ci>
<ci> ACoA </ci>
<ci> Mw_ACT </ci>
<ci> OD </ci>
<ci> PTACK_Kacoa </ci>
<ci> PTACK_Kpyr </ci>
<ci> PTACK_L </ci>
<ci> PTACK_Vmax </ci>
<ci> PTACK_n </ci>
<ci> PYR </ci>
<ci> uc </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_ACT_uptake' name='v_ACT_uptake' reversible='true'>
<listOfReactants>
<speciesReference species='ACT_ex' stoichiometry='1'/>
</listOfReactants>
<listOfModifiers>
<modifierSpeciesReference species='OD'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_ACT_uptake </ci>
<ci> ACT_ex </ci>
<ci> Acs_Kact </ci>
<ci> Acs_Vmax </ci>
<ci> Mw_ACT </ci>
<ci> OD </ci>
<ci> TF_ArcA </ci>
<ci> TF_CrpcAMP </ci>
<ci> TF_Fnr </ci>
<ci> uc </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_ADH' name='v_ADH' reversible='true'>
<listOfReactants>
<speciesReference species='NADH' stoichiometry='1'/>
<speciesReference species='AcAld' stoichiometry='1'/>
</listOfReactants>
<listOfModifiers>
<modifierSpeciesReference species='ETH'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_ADH </ci>
<ci> AcAld </ci>
<ci> ETH </ci>
<ci> Kacald_ADH </ci>
<ci> Keq_ADH </ci>
<ci> Keth_ADH </ci>
<ci> Knad_ADH </ci>
<ci> Knadh_ADH </ci>
<ci> NAD </ci>
<ci> NADH </ci>
<ci> Vmax_ADH </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_ALDH' name='v_ALDH' reversible='true'>
<listOfReactants>
<speciesReference species='NADH' stoichiometry='1'/>
<speciesReference species='ACoA' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='AcAld' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_ALDH </ci>
<ci> ACoA </ci>
<ci> AcAld </ci>
<ci> CoA </ci>
<ci> Kacald_ALDH </ci>
<ci> Kacoa_ALDH </ci>
<ci> Kcoa_ALDH </ci>
<ci> Keq_ALDH </ci>
<ci> Knad_ALDH </ci>
<ci> Knadh_ALDH </ci>
<ci> NAD </ci>
<ci> NADH </ci>
<ci> Vmax_ALDH </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Acs' name='v_Acs' reversible='true'>
<listOfProducts>
<speciesReference species='ACoA' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='ACT_ex'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Acs </ci>
<ci> ACT_ex </ci>
<ci> Acs_Kact </ci>
<ci> Acs_Vmax </ci>
<ci> TF_ArcA </ci>
<ci> TF_CrpcAMP </ci>
<ci> TF_Fnr </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Bio_ACoA' name='v_Bio_ACoA' reversible='true'>
<listOfReactants>
<speciesReference species='ACoA' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Bio_ACoA </ci>
<ci> ACoA </ci>
<ci> b_Bio_ACoA </ci>
<ci> k_Bio_ACoA </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Bio_AKG' name='v_Bio_AKG' reversible='true'>
<listOfReactants>
<speciesReference species='AKG' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Bio_AKG </ci>
<ci> AKG </ci>
<ci> b_Bio_AKG </ci>
<ci> k_Bio_AKG </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Bio_E4P' name='v_Bio_E4P' reversible='true'>
<listOfReactants>
<speciesReference species='E4P' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Bio_E4P </ci>
<ci> E4P </ci>
<ci> b_Bio_E4P </ci>
<ci> k_Bio_E4P </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Bio_G6P' name='v_Bio_G6P' reversible='true'>
<listOfReactants>
<speciesReference species='G6P' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Bio_G6P </ci>
<ci> G6P </ci>
<ci> b_Bio_G6P </ci>
<ci> k_Bio_G6P </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Bio_OAA' name='v_Bio_OAA' reversible='true'>
<listOfReactants>
<speciesReference species='OAA' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Bio_OAA </ci>
<ci> OAA </ci>
<ci> b_Bio_OAA </ci>
<ci> k_Bio_OAA </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Bio_PEP' name='v_Bio_PEP' reversible='true'>
<listOfReactants>
<speciesReference species='PEP' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Bio_PEP </ci>
<ci> PEP </ci>
<ci> b_Bio_PEP </ci>
<ci> k_Bio_PEP </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Bio_PG3' name='v_Bio_PG3' reversible='true'>
<listOfReactants>
<speciesReference species='PG3' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Bio_PG3 </ci>
<ci> PG3 </ci>
<ci> b_Bio_PG3 </ci>
<ci> k_Bio_PG3 </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Bio_PYR' name='v_Bio_PYR' reversible='true'>
<listOfReactants>
<speciesReference species='PYR' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Bio_PYR </ci>
<ci> PYR </ci>
<ci> b_Bio_PYR </ci>
<ci> k_Bio_PYR </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Bio_R5P' name='v_Bio_R5P' reversible='true'>
<listOfReactants>
<speciesReference species='Rib5' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Bio_R5P </ci>
<ci> Rib5 </ci>
<ci> b_Bio_R5P </ci>
<ci> k_Bio_R5P </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_CS' name='v_CS' reversible='true'>
<listOfReactants>
<speciesReference species='OAA' stoichiometry='1'/>
<speciesReference species='ACoA' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='ICT' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='AKG'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_CS </ci>
<ci> ACoA </ci>
<ci> AKG </ci>
<ci> CS_Kacoa </ci>
<ci> CS_Kakg </ci>
<ci> CS_Koaa </ci>
<ci> CS_Koaaacoa </ci>
<ci> CS_Vmax </ci>
<ci> OAA </ci>
<ci> TF_ArcA </ci>
<ci> TF_CrpcAMP </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Cya' name='v_Cya' reversible='true'>
<listOfProducts>
<speciesReference species='cAMP' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='EIIA_P'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Cya </ci>
<ci> Cya_KEIIA </ci>
<ci> Cya_Vmax </ci>
<ci> EIIA_P </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Cyd' name='v_Cyd' reversible='true'>
<listOfReactants>
<speciesReference species='QH2' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='Q' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Cyd </ci>
<ci> Km_Cyd_O2 </ci>
<ci> Km_Cyd_QH2 </ci>
<ci> O2 </ci>
<ci> QH2 </ci>
<ci> TF_ArcA </ci>
<ci> TF_Fnr </ci>
<ci> k_O2 </ci>
<ci> v_Cyd_max </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Cyo' name='v_Cyo' reversible='true'>
<listOfReactants>
<speciesReference species='QH2' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='Q' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Cyo </ci>
<ci> Km_Cyo_O2 </ci>
<ci> Km_Cyo_QH2 </ci>
<ci> O2 </ci>
<ci> QH2 </ci>
<ci> TF_ArcA </ci>
<ci> TF_Fnr </ci>
<ci> k_O2 </ci>
<ci> v_Cyo_max </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_ACoA' name='v_D_ACoA' reversible='true'>
<listOfReactants>
<speciesReference species='ACoA' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_ACoA </ci>
<ci> ACoA </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_AKG' name='v_D_AKG' reversible='true'>
<listOfReactants>
<speciesReference species='AKG' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_AKG </ci>
<ci> AKG </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_AcAld' name='v_D_AcAld' reversible='true'>
<listOfReactants>
<speciesReference species='AcAld' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_AcAld </ci>
<ci> AcAld </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_CraFBP' name='v_D_CraFBP' reversible='true'>
<listOfReactants>
<speciesReference species='CraFBP' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_CraFBP </ci>
<ci> CraFBP </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_CrpcAMP' name='v_D_CrpcAMP' reversible='true'>
<listOfReactants>
<speciesReference species='CrpcAMP' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_CrpcAMP </ci>
<ci> CrpcAMP </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_E4P' name='v_D_E4P' reversible='true'>
<listOfReactants>
<speciesReference species='E4P' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_E4P </ci>
<ci> E4P </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_FBP' name='v_D_FBP' reversible='true'>
<listOfReactants>
<speciesReference species='FBP' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_FBP </ci>
<ci> FBP </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_G6P' name='v_D_G6P' reversible='true'>
<listOfReactants>
<speciesReference species='G6P' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_G6P </ci>
<ci> G6P </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_GLCin' name='v_D_GLCin' reversible='true'>
<listOfReactants>
<speciesReference species='GLCin' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_GLCin </ci>
<ci> GLCin </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_GLX' name='v_D_GLX' reversible='true'>
<listOfReactants>
<speciesReference species='GLX' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_GLX </ci>
<ci> GLX </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_ICT' name='v_D_ICT' reversible='true'>
<listOfReactants>
<speciesReference species='ICT' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_ICT </ci>
<ci> ICT </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_MAL' name='v_D_MAL' reversible='true'>
<listOfReactants>
<speciesReference species='MAL' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_MAL </ci>
<ci> MAL </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_NADH' name='v_D_NADH' reversible='true'>
<listOfReactants>
<speciesReference species='NADH' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_NADH </ci>
<ci> NADH </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_OAA' name='v_D_OAA' reversible='true'>
<listOfReactants>
<speciesReference species='OAA' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_OAA </ci>
<ci> OAA </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_PEP' name='v_D_PEP' reversible='true'>
<listOfReactants>
<speciesReference species='PEP' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_PEP </ci>
<ci> PEP </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_PG3' name='v_D_PG3' reversible='true'>
<listOfReactants>
<speciesReference species='PG3' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_PG3 </ci>
<ci> PG3 </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_PG6' name='v_D_PG6' reversible='true'>
<listOfReactants>
<speciesReference species='PG6' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_PG6 </ci>
<ci> PG6 </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_PYR' name='v_D_PYR' reversible='true'>
<listOfReactants>
<speciesReference species='PYR' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_PYR </ci>
<ci> PYR </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_PdhRPYR' name='v_D_PdhRPYR' reversible='true'>
<listOfReactants>
<speciesReference species='PdhRPYR' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_PdhRPYR </ci>
<ci> PdhRPYR </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_Q' name='v_D_Q' reversible='true'>
<listOfReactants>
<speciesReference species='Q' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_Q </ci>
<ci> Q </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_QH2' name='v_D_QH2' reversible='true'>
<listOfReactants>
<speciesReference species='QH2' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_QH2 </ci>
<ci> QH2 </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_Rib5' name='v_D_Rib5' reversible='true'>
<listOfReactants>
<speciesReference species='Rib5' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_Rib5 </ci>
<ci> Rib5 </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_Ribu5' name='v_D_Ribu5' reversible='true'>
<listOfReactants>
<speciesReference species='Ribu5' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_Ribu5 </ci>
<ci> Ribu5 </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_S7P' name='v_D_S7P' reversible='true'>
<listOfReactants>
<speciesReference species='S7P' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_S7P </ci>
<ci> S7P </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_SUC' name='v_D_SUC' reversible='true'>
<listOfReactants>
<speciesReference species='SUC' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_SUC </ci>
<ci> SUC </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_Xyl5' name='v_D_Xyl5' reversible='true'>
<listOfReactants>
<speciesReference species='Xyl5' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_Xyl5 </ci>
<ci> Xyl5 </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_D_cAMP' name='v_D_cAMP' reversible='true'>
<listOfReactants>
<speciesReference species='cAMP' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_D_cAMP </ci>
<ci> cAMP </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_ETH_excretion' name='v_ETH_excretion' reversible='true'>
<listOfProducts>
<speciesReference species='ETH' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='AcAld'/>
<modifierSpeciesReference species='OD'/>
<modifierSpeciesReference species='NADH'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_ETH_excretion </ci>
<ci> AcAld </ci>
<ci> ETH </ci>
<ci> Kacald_ADH </ci>
<ci> Keq_ADH </ci>
<ci> Keth_ADH </ci>
<ci> Knad_ADH </ci>
<ci> Knadh_ADH </ci>
<ci> Mw_ETH </ci>
<ci> NAD </ci>
<ci> NADH </ci>
<ci> OD </ci>
<ci> Vmax_ADH </ci>
<ci> uc </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Emp1' name='v_Emp1' reversible='true'>
<listOfReactants>
<speciesReference species='FBP' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='PG3' stoichiometry='2'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Emp1 </ci>
<ci> Emp_Kfbp </ci>
<ci> Emp_Kpg3 </ci>
<ci> Emp_Vmax_f </ci>
<ci> Emp_Vmax_r </ci>
<ci> FBP </ci>
<ci> PG3 </ci>
<ci> TF_Cra </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Emp2' name='v_Emp2' reversible='true'>
<listOfReactants>
<speciesReference species='PG3' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='NADH' stoichiometry='1'/>
<speciesReference species='PEP' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Emp2 </ci>
<ci> Eno_Kpep </ci>
<ci> Eno_Kpg3 </ci>
<ci> Eno_Vmax_f </ci>
<ci> Eno_Vmax_r </ci>
<ci> PEP </ci>
<ci> PG3 </ci>
<ci> TF_Cra </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_FOR_excretion' name='v_FOR_excretion' reversible='true'>
<listOfProducts>
<speciesReference species='FOR' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='ACoA'/>
<modifierSpeciesReference species='PYR'/>
<modifierSpeciesReference species='OD'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_FOR_excretion </ci>
<ci> ACoA </ci>
<ci> CoA </ci>
<ci> FOR </ci>
<ci> Kacoa_Pfl </ci>
<ci> Kcoa_Pfl </ci>
<ci> Kfor_Pfl </ci>
<ci> Kpyr_Pfl </ci>
<ci> Mw_FOR </ci>
<ci> OD </ci>
<ci> PYR </ci>
<ci> TF_ArcA </ci>
<ci> TF_Fnr </ci>
<ci> Vmaxf_Pfl </ci>
<ci> Vmaxr_Pfl </ci>
<ci> uc </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_FRD' name='v_FRD' reversible='true'>
<listOfReactants>
<speciesReference species='MAL' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='SUC' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_FRD </ci>
<ci> Kfum_FRD </ci>
<ci> Ksuc_SDH </ci>
<ci> MAL </ci>
<ci> SUC </ci>
<ci> TF_Fnr </ci>
<ci> Vmaxr_SDH </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Fdp' name='v_Fdp' reversible='true'>
<listOfReactants>
<speciesReference species='FBP' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='G6P' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='PEP'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Fdp </ci>
<ci> FBP </ci>
<ci> Fdp_Kfbp </ci>
<ci> Fdp_Kpep </ci>
<ci> Fdp_L </ci>
<ci> Fdp_Vmax </ci>
<ci> Fdp_n </ci>
<ci> PEP </ci>
<ci> TF_Cra </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_G6PDH' name='v_G6PDH' reversible='true'>
<listOfReactants>
<speciesReference species='G6P' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='PG6' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_G6PDH </ci>
<ci> G6P </ci>
<ci> G6PDH_Kg6p </ci>
<ci> G6PDH_Knadp </ci>
<ci> G6PDH_Knadph_g6pinh </ci>
<ci> G6PDH_Knadph_nadphinh </ci>
<ci> G6PDH_Vmax </ci>
<ci> NADP </ci>
<ci> NADPH </ci>
<ci> TF_Cra </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_GLC_uptake' name='v_GLC_uptake' reversible='true'>
<listOfReactants>
<speciesReference species='GLC_ex' stoichiometry='1'/>
</listOfReactants>
<listOfModifiers>
<modifierSpeciesReference species='EIIA'/>
<modifierSpeciesReference species='EIIA_P'/>
<modifierSpeciesReference species='OD'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_GLC_uptake </ci>
<ci> EIIA </ci>
<ci> EIIA_P </ci>
<ci> GLC_ex </ci>
<ci> Mw_GLC </ci>
<ci> NPTS_Ki </ci>
<ci> NPTS_Ks </ci>
<ci> NPTS_Vmax </ci>
<ci> OD </ci>
<ci> PTS4_KEIIA </ci>
<ci> PTS4_Kglc </ci>
<ci> PTS4_Vmax </ci>
<ci> TF_CrpcAMP </ci>
<ci> uc </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Glk' name='v_Glk' reversible='true'>
<listOfReactants>
<speciesReference species='GLCin' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='G6P' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Glk </ci>
<ci> G6P </ci>
<ci> GLCin </ci>
<ci> Glk_KI </ci>
<ci> Glk_Ks </ci>
<ci> Glk_Vmax </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Growth' name='v_Growth' reversible='true'>
<listOfProducts>
<speciesReference species='OD' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Growth </ci>
<ci> OD </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_ICDH' name='v_ICDH' reversible='true'>
<listOfReactants>
<speciesReference species='ICT' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='AKG' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='PEP'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_ICDH </ci>
<ci> ICDH_Kict </ci>
<ci> ICDH_Kpep </ci>
<ci> ICDH_L </ci>
<ci> ICDH_Vmax </ci>
<ci> ICDH_n </ci>
<ci> ICT </ci>
<ci> PEP </ci>
<ci> TF_ArcA </ci>
<ci> TF_Cra </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Icl' name='v_Icl' reversible='true'>
<listOfReactants>
<speciesReference species='ICT' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='GLX' stoichiometry='1'/>
<speciesReference species='SUC' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='AKG'/>
<modifierSpeciesReference species='PG3'/>
<modifierSpeciesReference species='PEP'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Icl </ci>
<ci> AKG </ci>
<ci> ICT </ci>
<ci> Icl_Kakg </ci>
<ci> Icl_Kict </ci>
<ci> Icl_Kpep </ci>
<ci> Icl_Kpg3 </ci>
<ci> Icl_L </ci>
<ci> Icl_Vmax </ci>
<ci> Icl_n </ci>
<ci> PEP </ci>
<ci> PG3 </ci>
<ci> TF_Cra </ci>
<ci> TF_IclR </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_KGMAL' name='v_KGMAL' reversible='true'>
<listOfReactants>
<speciesReference species='AKG' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='NADH' stoichiometry='1'/>
<speciesReference species='SUC' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_KGMAL </ci>
<ci> AKG </ci>
<ci> KGMAL_Kakg </ci>
<ci> KGMAL_Vmax </ci>
<ci> TF_ArcA </ci>
<ci> TF_CrpcAMP </ci>
<ci> TF_Fnr </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_LAC_excretion' name='v_LAC_excretion' reversible='true'>
<listOfProducts>
<speciesReference species='LAC' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='PYR'/>
<modifierSpeciesReference species='NADH'/>
<modifierSpeciesReference species='OD'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_LAC_excretion </ci>
<ci> Km_NADH_LDH </ci>
<ci> Km_PYR_LDH </ci>
<ci> Mw_LAC </ci>
<ci> NADH </ci>
<ci> OD </ci>
<ci> PYR </ci>
<ci> Vmax_LDH </ci>
<ci> n_NADH_LDH </ci>
<ci> n_PYR_LDH </ci>
<ci> uc </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_LDH' name='v_LDH' reversible='true'>
<listOfReactants>
<speciesReference species='NADH' stoichiometry='1'/>
<speciesReference species='PYR' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_LDH </ci>
<ci> Km_NADH_LDH </ci>
<ci> Km_PYR_LDH </ci>
<ci> NADH </ci>
<ci> PYR </ci>
<ci> Vmax_LDH </ci>
<ci> n_NADH_LDH </ci>
<ci> n_PYR_LDH </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_MDH' name='v_MDH' reversible='true'>
<listOfReactants>
<speciesReference species='MAL' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='NADH' stoichiometry='1'/>
<speciesReference species='OAA' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_MDH </ci>
<ci> K_mal_MDH </ci>
<ci> K_nad_MDH </ci>
<ci> K_nadh_MDH </ci>
<ci> K_oaa_MDH </ci>
<ci> MAL </ci>
<ci> NAD </ci>
<ci> NADH </ci>
<ci> OAA </ci>
<ci> TF_CrpcAMP </ci>
<ci> Vmaxf_MDH </ci>
<ci> Vmaxr_MDH </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_MS' name='v_MS' reversible='true'>
<listOfReactants>
<speciesReference species='ACoA' stoichiometry='1'/>
<speciesReference species='GLX' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='MAL' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_MS </ci>
<ci> ACoA </ci>
<ci> GLX </ci>
<ci> MS_Kacoa </ci>
<ci> MS_Kglx </ci>
<ci> MS_Kglxacoa </ci>
<ci> MS_Vmax </ci>
<ci> TF_Cra </ci>
<ci> TF_IclR </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Mez' name='v_Mez' reversible='true'>
<listOfReactants>
<speciesReference species='MAL' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='PYR' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='cAMP'/>
<modifierSpeciesReference species='ACoA'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Mez </ci>
<ci> ACoA </ci>
<ci> MAL </ci>
<ci> Mez_Kacoa </ci>
<ci> Mez_Kcamp </ci>
<ci> Mez_Kmal </ci>
<ci> Mez_L </ci>
<ci> Mez_Vmax </ci>
<ci> Mez_n </ci>
<ci> cAMP </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_NPTS' name='v_NPTS' reversible='true'>
<listOfProducts>
<speciesReference species='GLCin' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='GLC_ex'/>
<modifierSpeciesReference species='EIIA'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_NPTS </ci>
<ci> EIIA </ci>
<ci> GLC_ex </ci>
<ci> NPTS_Ki </ci>
<ci> NPTS_Ks </ci>
<ci> NPTS_Vmax </ci>
<ci> TF_CrpcAMP </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Ndh' name='v_Ndh' reversible='true'>
<listOfReactants>
<speciesReference species='NADH' stoichiometry='1'/>
<speciesReference species='Q' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='QH2' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Ndh </ci>
<ci> Km_Ndh_Q </ci>
<ci> Km_Ndh_e2H2 </ci>
<ci> NADH </ci>
<ci> Q </ci>
<ci> TF_Fnr </ci>
<ci> v_Ndh_max </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Nuo' name='v_Nuo' reversible='true'>
<listOfReactants>
<speciesReference species='NADH' stoichiometry='1'/>
<speciesReference species='Q' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='QH2' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Nuo </ci>
<ci> Km_Nuo_Q </ci>
<ci> Km_Nuo_e2H2 </ci>
<ci> NADH </ci>
<ci> Q </ci>
<ci> TF_ArcA </ci>
<ci> TF_Fnr </ci>
<ci> v_Nuo_max </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_PDH' name='v_PDH' reversible='true'>
<listOfReactants>
<speciesReference species='PYR' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='NADH' stoichiometry='1'/>
<speciesReference species='ACoA' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='GLX'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_PDH </ci>
<ci> GLX </ci>
<ci> PDH_Kglx </ci>
<ci> PDH_Kpyr </ci>
<ci> PDH_KpyrI </ci>
<ci> PDH_L </ci>
<ci> PDH_Vmax </ci>
<ci> PDH_n </ci>
<ci> PYR </ci>
<ci> TF_ArcA </ci>
<ci> TF_PdhR </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_PGDH' name='v_PGDH' reversible='true'>
<listOfReactants>
<speciesReference species='PG6' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='Ribu5' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_PGDH </ci>
<ci> ATP </ci>
<ci> NADP </ci>
<ci> NADPH </ci>
<ci> PG6 </ci>
<ci> PGDH_K6pg </ci>
<ci> PGDH_Katpinh </ci>
<ci> PGDH_Knadp </ci>
<ci> PGDH_Knadphinh </ci>
<ci> PGDH_Vmax </ci>
<ci> mu </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_PTACK' name='v_PTACK' reversible='true'>
<listOfReactants>
<speciesReference species='ACoA' stoichiometry='1'/>
</listOfReactants>
<listOfModifiers>
<modifierSpeciesReference species='PYR'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_PTACK </ci>
<ci> ACoA </ci>
<ci> PTACK_Kacoa </ci>
<ci> PTACK_Kpyr </ci>
<ci> PTACK_L </ci>
<ci> PTACK_Vmax </ci>
<ci> PTACK_n </ci>
<ci> PYR </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_PTS1' name='v_PTS1' reversible='true'>
<listOfReactants>
<speciesReference species='PEP' stoichiometry='1'/>
<speciesReference species='EIIA' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='EIIA_P' stoichiometry='1'/>
<speciesReference species='PYR' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<minus/>
<apply>
<times/>
<ci> PTS1_k1 </ci>
<ci> PEP </ci>
<ci> EIIA </ci>
</apply>
<apply>
<times/>
<ci> PTS1_km1 </ci>
<ci> EIIA_P </ci>
<ci> PYR </ci>
</apply>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_PTS4' name='v_PTS4' reversible='true'>
<listOfReactants>
<speciesReference species='EIIA_P' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='G6P' stoichiometry='1'/>
<speciesReference species='EIIA' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='GLC_ex'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_PTS4 </ci>
<ci> EIIA_P </ci>
<ci> GLC_ex </ci>
<ci> PTS4_KEIIA </ci>
<ci> PTS4_Kglc </ci>
<ci> PTS4_Vmax </ci>
<ci> TF_CrpcAMP </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Pck' name='v_Pck' reversible='true'>
<listOfReactants>
<speciesReference species='OAA' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='PEP' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Pck </ci>
<ci> OAA </ci>
<ci> PEP </ci>
<ci> Pck_Koaa </ci>
<ci> Pck_Kpep </ci>
<ci> Pck_Vmax </ci>
<ci> TF_Cra </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Pfk' name='v_Pfk' reversible='true'>
<listOfReactants>
<speciesReference species='G6P' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='FBP' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='PEP'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Pfk </ci>
<ci> G6P </ci>
<ci> PEP </ci>
<ci> Pfk_Kg6p </ci>
<ci> Pfk_Kpep </ci>
<ci> Pfk_L </ci>
<ci> Pfk_Vmax </ci>
<ci> Pfk_n </ci>
<ci> TF_Cra </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Pfl' name='v_Pfl' reversible='true'>
<listOfReactants>
<speciesReference species='PYR' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='ACoA' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='FOR'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Pfl </ci>
<ci> ACoA </ci>
<ci> CoA </ci>
<ci> FOR </ci>
<ci> Kacoa_Pfl </ci>
<ci> Kcoa_Pfl </ci>
<ci> Kfor_Pfl </ci>
<ci> Kpyr_Pfl </ci>
<ci> PYR </ci>
<ci> TF_ArcA </ci>
<ci> TF_Fnr </ci>
<ci> Vmaxf_Pfl </ci>
<ci> Vmaxr_Pfl </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Ppc' name='v_Ppc' reversible='true'>
<listOfReactants>
<speciesReference species='PEP' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='OAA' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='FBP'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Ppc </ci>
<ci> FBP </ci>
<ci> PEP </ci>
<ci> Ppc_Kfbp </ci>
<ci> Ppc_Kpep </ci>
<ci> Ppc_L </ci>
<ci> Ppc_Vmax </ci>
<ci> Ppc_n </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Pps' name='v_Pps' reversible='true'>
<listOfReactants>
<speciesReference species='PYR' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='PEP' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Pps </ci>
<ci> PEP </ci>
<ci> PYR </ci>
<ci> Pps_Kpep </ci>
<ci> Pps_Kpyr </ci>
<ci> Pps_L </ci>
<ci> Pps_Vmax </ci>
<ci> Pps_n </ci>
<ci> TF_Cra </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Pyk' name='v_Pyk' reversible='true'>
<listOfReactants>
<speciesReference species='PEP' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='PYR' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='FBP'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Pyk </ci>
<ci> FBP </ci>
<ci> PEP </ci>
<ci> Pyk_Kfbp </ci>
<ci> Pyk_Kpep </ci>
<ci> Pyk_L </ci>
<ci> Pyk_Vmax </ci>
<ci> Pyk_n </ci>
<ci> TF_Cra </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_R5PI' name='v_R5PI' reversible='true'>
<listOfReactants>
<speciesReference species='Ribu5' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='Rib5' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_R5PI </ci>
<ci> R5PI_Keq </ci>
<ci> R5PI_Vmax </ci>
<ci> Rib5 </ci>
<ci> Ribu5 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_Ru5P' name='v_Ru5P' reversible='true'>
<listOfReactants>
<speciesReference species='Ribu5' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='Xyl5' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_Ru5P </ci>
<ci> Ribu5 </ci>
<ci> Ru5P_Keq </ci>
<ci> Ru5P_Vmax </ci>
<ci> Xyl5 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_SDH' name='v_SDH' reversible='true'>
<listOfReactants>
<speciesReference species='SUC' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='MAL' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_SDH </ci>
<ci> Kfum_SDH </ci>
<ci> Ksuc_SDH </ci>
<ci> MAL </ci>
<ci> SUC </ci>
<ci> TF_ArcA </ci>
<ci> TF_CrpcAMP </ci>
<ci> TF_Fnr </ci>
<ci> Vmaxf_SDH </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_SUC_excretion' name='v_SUC_excretion' reversible='true'>
<listOfProducts>
<speciesReference species='SUC_ex' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='SUC'/>
<modifierSpeciesReference species='OD'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_SUC_excretion </ci>
<ci> Mw_SUC </ci>
<ci> OD </ci>
<ci> SUC </ci>
<ci> SUC_trans_Km_suc </ci>
<ci> SUC_trans_Vmax </ci>
<ci> uc </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_SUC_trans' name='v_SUC_trans' reversible='true'>
<listOfReactants>
<speciesReference species='SUC' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_SUC_trans </ci>
<ci> SUC </ci>
<ci> SUC_trans_Km_suc </ci>
<ci> SUC_trans_Vmax </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_TA' name='v_TA' reversible='true'>
<listOfReactants>
<speciesReference species='PG3' stoichiometry='1'/>
<speciesReference species='S7P' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='E4P' stoichiometry='1'/>
<speciesReference species='G6P' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_TA </ci>
<ci> E4P </ci>
<ci> G6P </ci>
<ci> PG3 </ci>
<ci> S7P </ci>
<ci> TA_Keq </ci>
<ci> TA_Vmax </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_TF_CraFBP' name='v_TF_CraFBP' reversible='true'>
<listOfProducts>
<speciesReference species='CraFBP' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='FBP'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_TF_CraFBP </ci>
<ci> Cra </ci>
<ci> CraFBP </ci>
<ci> FBP </ci>
<ci> TF_CraFBP_Kfbp </ci>
<ci> TF_CraFBP_n </ci>
<ci> TF_CraFBP_scale </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_TF_PdhRPYR' name='v_TF_PdhRPYR' reversible='true'>
<listOfProducts>
<speciesReference species='PdhRPYR' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='PYR'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_TF_PdhRPYR </ci>
<ci> PYR </ci>
<ci> PdhR </ci>
<ci> PdhRPYR </ci>
<ci> TF_PdhRPYR_Kpyr </ci>
<ci> TF_PdhRPYR_n </ci>
<ci> TF_PdhRPYR_scale </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_TF_cAMPCrp' name='v_TF_cAMPCrp' reversible='true'>
<listOfProducts>
<speciesReference species='CrpcAMP' stoichiometry='1'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species='cAMP'/>
</listOfModifiers>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_TF_cAMPCrp </ci>
<ci> Crp </ci>
<ci> CrpcAMP </ci>
<ci> TF_cAMPCrp_Kcamp </ci>
<ci> TF_cAMPCrp_n </ci>
<ci> TF_cAMPCrp_scale </ci>
<ci> cAMP </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_TKa' name='v_TKa' reversible='true'>
<listOfReactants>
<speciesReference species='Rib5' stoichiometry='1'/>
<speciesReference species='Xyl5' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='S7P' stoichiometry='1'/>
<speciesReference species='PG3' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_TKa </ci>
<ci> PG3 </ci>
<ci> Rib5 </ci>
<ci> S7P </ci>
<ci> TKa_Keq </ci>
<ci> TKa_Vmax </ci>
<ci> Xyl5 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_TKb' name='v_TKb' reversible='true'>
<listOfReactants>
<speciesReference species='Xyl5' stoichiometry='1'/>
<speciesReference species='E4P' stoichiometry='1'/>
</listOfReactants>
<listOfProducts>
<speciesReference species='G6P' stoichiometry='1'/>
<speciesReference species='PG3' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_TKb </ci>
<ci> E4P </ci>
<ci> G6P </ci>
<ci> PG3 </ci>
<ci> TKb_Keq </ci>
<ci> TKb_Vmax </ci>
<ci> Xyl5 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_cAMPdegr' name='v_cAMPdegr' reversible='true'>
<listOfReactants>
<speciesReference species='cAMP' stoichiometry='1'/>
</listOfReactants>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_cAMPdegr </ci>
<ci> cAMP </ci>
<ci> cAMPdegr_KcAMP </ci>
<ci> cAMPdegr_Vmax </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id='v_syn_QH2' name='v_syn_QH2' reversible='true'>
<listOfProducts>
<speciesReference species='QH2' stoichiometry='1'/>
</listOfProducts>
<kineticLaw>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<ci> Function_for_v_syn_QH2 </ci>
<ci> mu </ci>
<ci> p_syn_QH2 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
</listOfReactions>
</model>
</sbml>
Simulation of KIMOMODELID40.xml |
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| Notes |
Kinetic model source: http://www.cadlive.jp/cadlive_main/Softwares/KineticModel/Ecolimetabolism.html.
|
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| Software | MATLAB (MathWorks) was used for all simulations. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| BioModels or JWS Online ID | — | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Export metadata |
RDF:
metadataModelEntryID40.rdf
XML: metadataModelEntryID40.xml Plain text: metadataModelEntryID40.txt |
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AcAld
Share
|
Cite Model EntryID 40
Cite Model EntryID 40
| APA |
KiMoSys (https://kimosys.org). (2018, December 21). Model EntryID 40 (Escherichia coli). https://kimosys.org/repository/101/associated_models/40
|
|
| MLA |
KiMoSys (https://kimosys.org). "Model EntryID 40 (Escherichia coli)." 2024, kimosys.org/repository/101/associated_models/40.
|
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| ISO-690 |
KiMoSys (https://kimosys.org). Model EntryID 40 (Escherichia coli). [online], [Accessed 21 December 2024]. Available from: https://kimosys.org/repository/101/associated_models/40
|
|
| BibTeX |
@misc{ KiMoSysModelEntryID40,
author = "{KiMoSys (https://kimosys.org)}",
title = "Model EntryID 40 (Escherichia coli)",
url = "https://kimosys.org/repository/101/associated_models/40",
note = "[Online; accessed 21-December-2024]"
}
|
|
Related Model(s): AccessID 13 | AccessID 16 | AccessID 25 | AccessID 36 | AccessID 38 | AccessID 42 | AccessID 43 | AccessID 44 | AccessID 45
Submission and curation
Entered by:
Administrator KiMoSysFirst name: Administrator
Affiliation: INESC-ID/IST
Homepage: http://kdbio.inesc-id.pt/kimosys
Interests: mathematical modeling, accessible data, use of data
Created: 2018-07-19 15:05:36 UTC
Updated: 2018-07-20 16:25:00 UTC
Version: 1
Status: (reviewed) 2018-07-19 15:07:10 UTC
Views: 318
Downloads: 157